ArticleDose-response : a publication of International Hormesis Society2011
Residential radon appears to prevent lung cancer.
Article in Dose-response : a publication of International Hormesis Society, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.
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Who cites it
25 citing papers in PubMed, 1 synthesis or guideline pooled it, 57 citations in OpenAlex.
- Meta-analysis of thirty-two case-control and two ecological radon studies of lung cancer.Journal of radiation research · 2018Pooled it
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- Indoor Radon Concentration and Risk Assessment in 27 Districts of a Public Healthcare Company in Naples, South Italy.Life (Basel, Switzerland) · 2021Article
- Residential Radon in Manizales, Colombia: Results of a Pilot Study.International journal of environmental research and public health · 2021Article
- An Investigation into Indoor Radon Concentrations in Certified Passive House Homes.International journal of environmental research and public health · 2020Article
- Genomic Instability and Carcinogenesis of Heavy Charged Particles Radiation: Clinical and Environmental Implications.Medicina (Kaunas, Lithuania) · 2019Review
- Radiation-hormesis phenotypes, the related mechanisms and implications for disease prevention and therapy.Journal of cell communication and signaling · 2014Article
- Commentary: ethical issues of current health-protection policies on low-dose ionizing radiation.Dose-response : a publication of International Hormesis Society · 2014Article
- First generation stochastic gene episilencing (step1) model and applications to in vitro carcinogen exposure.Dose-response : a publication of International Hormesis Society · 2013Article
- Low-dose gamma-radiation inhibits benzo[a]pyrene-induced lung adenoma development in a/j mice.Dose-response : a publication of International Hormesis Society · 2012Article
- Small γ-Ray Doses Prevent Rather than Increase Lung Tumors in Mice.Dose-response : a publication of International Hormesis Society · 2012Article
- The new radiobiology: returning to our roots.Dose-response : a publication of International Hormesis Society · 2012Article
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- Epidemiologic Studies Cannot Reveal the True Shape of the Dose-Response Relationship for Radon-Induced Lung Cancer.Dose-response : a publication of International Hormesis SocietyArticle
- Health Impacts of Low-Dose Ionizing Radiation: Current Scientific Debates and Regulatory Issues.Dose-response : a publication of International Hormesis SocietyReview
- Treatment of Cancer and Inflammation With Low-Dose Ionizing Radiation: Three Case Reports.Dose-response : a publication of International Hormesis SocietyArticle
Corrections and comments
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Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Residential radon has been found to be associated with lung cancer in epidemiological/ecological studies and the researchers have inappropriately concluded that residential radon causes lung cancer. Their conclusion relates to the linear-no-threshold (LNT) hypothesis-based, risk-assessment paradigm; however, the LNT hypothesis has been invalidated in numerous studies. It is shown in this paper that our hormetic relative risk (HRR) model is consistent with lung cancer data where detailed measurements of radon in each home were carried out. Based on the HRR model, low-level radon radioactive progeny is credited for activated natural protection (ANP) against lung cancer including smoking-related lung cancer. The proportion B(x) (benefit function) of ANP beneficiaries increases as the average radon level x increases to near the Environmental Protection Agency's action level of 4 picocuries/L (approximately 150 Bq m(-3)). As the average level of radon increases to somewhat above the action level, ANP beneficiaries progressively decrease to zero (B(x) decreases to 0), facilitating the occurrence of smoking-related lung cancers as well as those related to other less important risk factors. Thus, residential radon does not appear to cause lung cancer but rather to protect, in an exposure-level-dependent manner, from its induction by other agents (e.g., cigarette-smoke-related carcinogens).
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.