Evidence map›Paper›PMID 22461745›Full record

ReviewThe Yale journal of biology and medicine2012

Targeted molecular imaging of angiogenesis in PET and SPECT: a review.

Mitchel R Stacy, Mark W Maxfield, Albert J Sinusas

Open access · greenAbstract readReview
In one paragraph

Review in The Yale journal of biology and medicine, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 1 pooled it
3.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 1 synthesis or guideline pooled it, 58 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Scandium-44: Diagnostic Feasibility in Tumor-Related Angiogenesis.International journal of molecular sciences · 2023
    Review
  6. Review
  7. Review
  8. Review
  9. What can be and what cannot be accomplished with PET to detect and characterize atherosclerotic plaques.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2018
    Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Review
  16. Emerging Imaging Modalities in Regenerative Medicine.Current pathobiology reports · 2015
    Review
  17. Review
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Mitchel R StacySection of Cardiovascular Medicine, Department of Internal Medicine, Yale School of Medicine, New Haven, CT, USA. mitchel.stacy@yale.edu
Mark W Maxfield
Albert J Sinusas
Yale University · US

Funding

Training In Multi-modality Molecular & Translational Cardiovascular ImagingT32HL098069 · NHLBI · YALE UNIVERSITY · PI JAMES S DUNCAN, Georges El Fakhri · 2010 to 2026
$5.2M
Non-Invasive Methods for Imaging Myocardial AngiogenesisR01HL065662 · NHLBI · YALE UNIVERSITY · PI SINUSAS, ALBERT J · 2001 to 2009
$3.2M
NHLBI NIH HHS R01 HL065662NHLBI NIH HHS R01 HL65662NHLBI NIH HHS T32 HL098069
6 · The paper itself

Abstract

Over the past few decades, there have been significant advancements in the imaging techniques of positron emission tomography (PET) and single photon emission tomography (SPECT). These changes have allowed for the targeted imaging of cellular processes and the development of hybrid imaging systems (e.g., SPECT/CT and PET/CT), which provide both functional and structural images of biological systems. One area that has garnered particular attention is angiogenesis as it relates to ischemic heart disease and limb ischemia. Though the aforementioned techniques have benefits and consequences, they enable scientists and clinicians to identify regions that are vulnerable to or have been exposed to ischemic injury via non-invasive means. This literature review highlights the advancements in molecular imaging techniques and specific probes as they pertain to the process of angiogenesis in cardiovascular disease.

Indexed as

Positron-Emission TomographyTomography, Emission-Computed, Single-PhotonHumansIntegrinsMolecular ImagingNeovascularization, PathologicReceptors, Vascular Endothelial Growth FactorIntegrinsReceptors, Vascular Endothelial Growth FactorangiogenesisCThind limb ischemiamolecular imagingmyocardial ischemiaPETSPECT

Identifiers

PMID22461745
PMCPMC3313541
OpenAlexW1708360114

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.