Evidence map›Paper›PMID 22461680›Full record

ArticleJournal of clinical microbiology2012

Correlation of clinical outcomes with β-glucan levels in patients with invasive candidiasis.

Charles R Sims, Siraya Jaijakul, John Mohr, Jose Rodriguez, Malcolm Finkelman, Luis Ostrosky-Zeichner

Open access · bronzeAbstract read
In one paragraph

Article in Journal of clinical microbiology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 60 citations in OpenAlex.

  1. Trial
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  7. Interaction Between Dendritic Cells andFrontiers in cellular and infection microbiology · 2020
    Article
  8. β-d-Glucan andMedical journal, Armed Forces India · 2019
    Article
  9. Article
  10. Article
  11. Article
  12. Experience with β-D-Glucan Assay in the Management of Critically ill Patients with High Risk of Invasive Candidiasis: An Observational Study.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2018
    Article
  13. Review
  14. Review
  15. Article
  16. Article
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  18. Observational
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Charles R SimsLaboratory of Mycology Research, Division of Infectious Diseases, University of Texas Health Science Center at Houston, Houston, Texas, USA.
Siraya Jaijakul
John Mohr
Jose Rodriguez
Malcolm Finkelman
Luis Ostrosky-Zeichner
The University of Texas Health Science Center at Houston · USCubist Pharmaceuticals (United States) · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The correlation of β-glucan (BG) levels with clinical outcomes in invasive candidiasis (IC) remains unknown. Patients with proven IC were followed prospectively from diagnosis to outcome with twice-weekly serum BG sampling. Correlation of BG with clinical outcome was assessed in each patient. BG levels tend to decrease in successfully treated patients and increase in treatment failures. BG levels may be useful as surrogates for outcome evaluation of IC.

Indexed as

AdolescentAdultAgedAged, 80 and overAntifungal Agentsbeta-GlucansCandidiasis, InvasiveFemaleFollow-Up StudiesHumansMaleMiddle AgedProspective StudiesSerumTreatment OutcomeYoung AdultAntifungal Agentsbeta-Glucans

Identifiers

PMID22461680
PMCPMC3372136
OpenAlexW2147234516

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.