Evidence map›Paper›PMID 22461645›Full record

ReviewScience translational medicine2012

Applying what we know to accelerate cancer prevention.

Graham A Colditz, Kathleen Y Wolin, Sarah Gehlert

Abstract readReview
In one paragraph

Review in Science translational medicine, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 125 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
125citing papers in PubMed, 1 pooled it
11.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

125 citing papers in PubMed, 1 synthesis or guideline pooled it, 270 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Clinical Decision Support with or without Shared Decision Making to Improve Preventive Cancer Care: A Cluster-Randomized Trial.Medical decision making : an international journal of the Society for Medical Decision Making · 2022
    Trial
  4. Trial
  5. Trial
  6. Article
  7. Article
  8. Article
  9. "If I Start [Primary Prevention] Now, I Can Prevent [Cancer]": College Students Endorse Cancer Prevention Education.Journal of cancer education : the official journal of the American Association for Cancer Education · 2025
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. The Past and Future of Inflammation as a Target to Cancer Prevention.Cancer prevention research (Philadelphia, Pa.) · 2024
    Article

65 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Graham A ColditzAlvin J. Siteman Cancer Center and Division of Public Health Sciences, Department of Surgery, Washington University, St. Louis, MO 63110, USA. colditzg@wudosis.wustl.edu
Kathleen Y Wolin
Sarah Gehlert
Washington University in St. Louis · USGeorge Washington University · US

Funding

Washington University Center for Cellular ImagingP30CA091842 · NCI · WASHINGTON UNIVERSITY · PI TIMOTHY J. EBERLEIN · 2001 to 2026
$128.0M
Worksite Policies and neighborhood Influences on Obesity and Cancer RiskU54CA155496 · NCI · WASHINGTON UNIVERSITY · PI COLDITZ, GRAHAM A. · 2011 to 2016
$9.0M
Training ProgramU54CA153460 · NCI · WASHINGTON UNIVERSITY · PI COLDITZ, GRAHAM A. · 2010 to 2015
$5.3M
NCI NIH HHS P30 CA091842NCI NIH HHS P30CA091842NCI NIH HHS U54 CA153460NCI NIH HHS U54 CA155496PHS HHS U54-153460PHS HHS U54-155496
6 · The paper itself

Abstract

More than half of the cancer occurring today is preventable by applying knowledge that we already have. Tobacco, obesity, and physical inactivity are the modifiable causes of cancer that generate the most disease. Cancer burden can be reduced by alterations in individual and population behaviors and by public health efforts as long as these changes are driven by sound scientific knowledge and social commitment to change. The obstacles to these efforts are societal and arise from the organization of institutions, including academia, and in the habits of daily life. To achieve maximal possible cancer prevention, we will need better ways to implement what we know and improved infrastructure that will better incentivize and support transdisciplinary, multilevel research and successful intervention.

Indexed as

Health Knowledge, Attitudes, PracticeBiomedical ResearchHumansInterdisciplinary StudiesNeoplasmsSocioeconomic FactorsTreatment Outcome

Identifiers

PMID22461645
PMCPMC3343638
OpenAlexW2162326400

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.