Evidence map›Paper›PMID 22461529›Full record

ArticleClinical and vaccine immunology : CVI2012

Added value of use of a purified protein derivative-based enzyme-linked immunosorbent spot assay for patients with Mycobacterium bovis BCG infection after intravesical BCG instillations.

Karen A Heemstra, Ailko W J Bossink, Roan Spermon, John J M Bouwman, Robert van der Kieft, Steven F T Thijsen

Open access · diamondAbstract readCase ReportsEvaluation Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Clinical and vaccine immunology : CVI, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Karen A HeemstraDiakonessenhuis Utrecht, Medical Microbiology and Immunology, Utrecht, The Netherlands. K.A.Heemstra@umcutrecht.nl
Ailko W J Bossink
Roan Spermon
John J M Bouwman
Robert van der Kieft
Steven F T Thijsen
Diakonessenhuis hospital · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this case series, we describe four cases in which the use of gamma interferon release assays with purified protein derivative (PPD) as a stimulating antigen was able to demonstrate PPD-specific immune activation. This may help to improve the adequate diagnosis of (systemic) Mycobacterium bovis BCG infections after intravesical BCG instillations for bladder carcinoma.

Indexed as

TuberculinAdministration, IntravesicalAgedAged, 80 and overHumansInterferon-gamma Release TestsMaleMiddle AgedMycobacterium bovisTuberculosisUrinary Bladder NeoplasmsTuberculin

Identifiers

PMID22461529
PMCPMC3370454
OpenAlexW2147916760

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.