Evidence map›Paper›PMID 22461331›Full record

ArticleStroke2012

Preconditioning the brain: moving on to the next frontier of neurotherapeutics.

Sebastian Koch, Ralph L Sacco, Miguel A Perez-Pinzon

Abstract readEditorial
In one paragraph

Article in Stroke, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Review
  6. Article
  7. The Janus Face of VEGF in Stroke.International journal of molecular sciences · 2018
    Review
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Ischemic preconditioning and clinical scenarios.Current opinion in neurology · 2013
    Review
  17. Review
  18. Genetic animal models of preconditioning.Translational stroke research · 2013
    Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Sebastian Koch
Ralph L Sacco
Miguel A Perez-Pinzon

Funding

ISCHEMIC PRECONDITIONING: MECHANISMS OF NEUROPROTECTIONR01NS034773 · NINDS · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI MIGUEL A PEREZ-PINZON · 2003 to 2026
$6.7M
MECHANISMS OF NEUROPROTECTION AGAINST CARDIAC ARRESTR01NS045676 · NINDS · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI PEREZ-PINZON, MIGUEL A · 2004 to 2024
$5.1M
NINDS NIH HHS R01 NS034773NINDS NIH HHS R01 NS045676
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

BrainIschemic PreconditioningAnimalsEducationHumansNervous System DiseasesUnited States

Identifiers

PMID22461331
PMCPMC4086165

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.