ArticleClinical cases in mineral and bone metabolism : the official journal of the Italian Society of Osteoporosis, Mineral Metabolism, and Skeletal Diseases2009
Bone fragility and imaging techniques.
Article in Clinical cases in mineral and bone metabolism : the official journal of the Italian Society of Osteoporosis, Mineral Metabolism, and Skeletal Diseases, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
28 citing papers in PubMed, 54 citations in OpenAlex.
- Trial
- Comparison of Tibial Intramedullary Nailing Guided by Digital Technology Versus Conventional Method: A Prospective Study.Medical science monitor : international medical journal of experimental and clinical research · 2017Trial
- Opportunistic osteoporosis screening on FDG PET/CT scans in breast carcinoma: a comparison with DXA.Asia Oceania journal of nuclear medicine & biology · 2026Article
- Radiofrequency Echographic Multi Spectrometry-A Novel Tool in the Diagnosis of Osteoporosis and Prediction of Fragility Fractures: A Systematic Review.Diagnostics (Basel, Switzerland) · 2025Review
- Osteoporosis incidence and its associated factors in the older Korean population: findings from a population-based cohort study.Archives of osteoporosis · 2024Article
- Reference Intervals for Bone Impact Microindentation in Healthy Adults: A Multi-Centre International Study.Calcified tissue international · 2023Article
- Endocrinal metabolic regulation on the skeletal system in post-menopausal women.Frontiers in physiology · 2022Review
- Association of secondary displacement of distal radius fractures with cortical bone quality at the distal radius.Archives of orthopaedic and trauma surgery · 2021Article
- A Review on Multiscale Bone Damage: From the Clinical to the Research Perspective.Materials (Basel, Switzerland) · 2021Review
- Diabetes and Bone Fragility.Diabetes therapy : research, treatment and education of diabetes and related disorders · 2021Review
- Article
- Bone Microarchitecture and Distal Radius Fracture Pattern Complexity.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2019Article
- Optimizing Accuracy of Proximal Femur Elastic Modulus Equations.Annals of biomedical engineering · 2019Article
- Prediction of lumbar vertebral body compressive strength of overweight and obese older adults using morphed subject-specific finite-element models to evaluate the effects of weight loss.Aging clinical and experimental research · 2019Article
- Quantitative imaging techniques for the assessment of osteoporosis and sarcopenia.Quantitative imaging in medicine and surgery · 2018Review
- Clinical utilities of quantitative ultrasound in osteoporosis associated with inflammatory rheumatic diseases.Quantitative imaging in medicine and surgery · 2018Review
- Cortical and trabecular morphology is altered in the limb bones of mice artificially selected for faster skeletal growth.Scientific reports · 2017Article
- Peripheral quantitative computed tomography (pQCT) for the assessment of bone strength in most of bone affecting conditions in developmental age: a review.Italian journal of pediatrics · 2016Review
- Bone strength and muscle properties in postmenopausal women with and without a recent distal radius fracture.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2015Article
- Comparative Analysis of Linear and Angular Measurements on Digital Orthopantomogram with Calcaneus Bone Mineral Density.Journal of clinical and diagnostic research : JCDR · 2015Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Bone fragility is a silent condition that increases bone fracture risk, enhanced by low bone mass and microarchitecture deterioration of bone tissue that lead to osteoporosis. Fragility fractures are the major clinical manifestation of osteoporosis.A large body of epidemiological data indicates that the current standard for predicting fragility fracture risk is an areal BMD (aBMD) measurement by DXA. Although mineral density measurements assess the quantity of bone, the quality of the tissue is an important predictor of fragility. Thus, bone strength is explained not only by BMD but also by macrostructural and microstructural characteristics of bone tissue. Imaging diagnostics, through the use of X-rays, DXA, Ultrasonography, CT and MR, provides methods for diagnosis and characterization of fractures, and semi- and quantitative methods for assessment of bone consistency and strength, that become precious for bone fragility clinical management if they are integrated by clinical risk factors. The last employment of sophisticated non-invasively imaging techniques in clinical research as high-resolution CT (hrCT), microCT (μ-CT), high-resolution MR (hrMR) and, microRM (μRM), combined with finite element analysis methods, open to new challenges in a better bone strength assessment to enhance the comprehension of biomechanical parameters and the prediction of fragility fractures.
Identifiers
22461252PMC2811356W1492708336What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.