ArticleNature2012
Drug development: Raise standards for preclinical cancer research.
Article in Nature, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1,089 papers, 9 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1,089 citing papers in PubMed, 9 syntheses or guidelines pooled it.
- Pooled it
- Good Practice Guideline for Preclinical Alcohol Research: The STRINGENCY Framework.Current topics in behavioral neurosciences · 2025Guideline
- Magnetic resonance imaging-based machine learning classification of schizophrenia spectrum disorders: a meta-analysis.Psychiatry and clinical neurosciences · 2024Pooled it
- Self-reporting with checklists in artificial intelligence research on medical imaging: a systematic review based on citations of CLAIM.European radiology · 2024Pooled it
- Meningioma animal models: a systematic review and meta-analysis.Journal of translational medicine · 2023Pooled it
- Methods for Heart Rate Variability Biofeedback (HRVB): A Systematic Review and Guidelines.Applied psychophysiology and biofeedback · 2023Pooled it
- Pooled it
- The optimal transplantation strategy of umbilical cord mesenchymal stem cells in spinal cord injury: a systematic review and network meta-analysis based on animal studies.Stem cell research & therapy · 2022Pooled it
- Quantifying research waste in ecology.Nature ecology & evolution · 2022Pooled it
- Correspondence to: AdipoRon promotes angiogenesis in B-cell leukemia by modulating pro-angiogenic factors through AdipoR1.Molecular biology reports · 2026Article
- Reproducibility in biomedical research.Nature medicine · 2026Review
- Artificial intelligence in biomarker discovery for diseases: diagnostic and therapeutic prospects.Signal transduction and targeted therapy · 2026Review
- Reproducibility in Studies on Dental Restorative Materials: A Critical Review.Materials (Basel, Switzerland) · 2026Review
- Localized immunotherapy via dissolving microneedles for the prevention of breast cancer recurrence.Drug delivery and translational research · 2026Review
- From bench to bedside: Overcoming translational hurdles in nanoparticle research with pharmacokinetic modeling.Bioengineering & translational medicine · 2026Review
- Multi-Target Antitumor Effects of Natural Products and Approved Drug Repurposing in Non-Small Cell Lung Cancer: Advances in Mechanisms, Combination Regimens, Delivery System Optimization, and Clinical Challenges.International journal of molecular sciences · 2026Review
- Methodological Considerations in Interpreting IL-15 Plus Thymosin α1 Therapy for Hepatocellular Carcinoma.Journal of gastroenterology and hepatology · 2026Article
- The Uptake of Preregistration, and Its Impact on the Proportion of Supported Hypotheses, in Sports Science.Sports medicine (Auckland, N.Z.) · 2026Article
- Cross-tissue immune profiling of APOE ε4 reveals early dysregulation in Alzheimer's disease.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026Article
- Three-dimensional spheroid models in breast cancer: tumor microenvironment complexity, cancer stem cell-driven resistance, and translational model integration.Journal of translational medicine · 2026Review
1,029 more citing papers are in PubMed but not listed here.
Corrections and comments
- Commented on by
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
PubMed holds no abstract for this paper.
Indexed as
Identifiers
22460880What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.