ReviewVirulence
Targeting of the central nervous system by Listeria monocytogenes.
Review in Virulence. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 90 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
90 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Early trigeminal nerve involvement in Listeria monocytogenes rhombencephalitis: case series and systematic review.Journal of neurology · 2017Pooled it
- The global burden of listeriosis: a systematic review and meta-analysis.The Lancet. Infectious diseases · 2014Pooled it
- What is the incubation period for listeriosis?BMC infectious diseases · 2013Pooled it
- Rapid CSF Molecular Diagnosis ofDiagnostics (Basel, Switzerland) · 2026Article
- Aggressive brainstem listeria abscess in an immunocompetent individual: A case report.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026Article
- Three metabolic pathways replenishing the one-carbon pool collectively support growth and virulence ofeLife · 2026Article
- Rare Listeria monocytogenes brain abscess presenting as a tunnel-like lesion in an immunocompromised patient.Acta neurologica Belgica · 2026Article
- Listeria rhombencephalitis in an alcoholic man; A case report and review of literature.eNeurologicalSci · 2026Article
- Synergistic Roles of InlA, InlB and LLO in the Infection of Trigeminal Ganglion Neurons by Ovine-DerivedAnimals : an open access journal from MDPI · 2026Article
- A pore-forming toxin initiates ABI1 complex switching to promote bacterial cell-to-cell spread.Nature communications · 2026Article
- An Unusual Case ofInfectious disease reports · 2026Article
- Molecular Characterization ofInternational journal of women's health · 2026Article
- Listeriosis - a retrospective study of 5 years on risk factors and clinical outcomes at a tertiary care hospital in Islamabad, Pakistan.Access microbiology · 2026Article
- Risk factors and outcomes of emerging Listeria monocytogenes infection in Pakistan: Insights from a tertiary care hospital.PloS one · 2026Article
- Inappropriate Antimicrobial Regimen Leading to RecurrentInfection and drug resistance · 2026Article
- Article
- Polyphenols Bioactive Metabolites, and Their Anti-Biofilm and Neuroprotective Potential.Foods (Basel, Switzerland) · 2025Review
- Bioprotective Strategies to ControlInternational journal of molecular sciences · 2025Review
- Review
- Clinical Presentations and Nosocomial Infections of Neurolisteriosis.The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2025Review
30 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Among bacteria that reach the central nervous system (CNS), Listeria monocytogenes (Lm) is one of deadliest, in human and ruminant. This facultative intracellular bacterium has the particularity to induce meningitis, meningoencephalitis and rhombencephalitis. Mechanisms by which Lm accesses the CNS remain poorly understood, but two major routes of infection have been proposed, based on clinical, in vitro and in vivo observations. A retrograde neural route is likely to occur in ruminants upon crossing of the oral epithelium, and this probably accounts for the observation that Lm induces almost exclusively rhombencephalitis in these animals. In contrast, the hematogenous route is likely the most frequent in human, in whom bacteria circulating in the blood, either free or associated with leukocytes are thought to breach the blood-brain barrier. New animal models that faithfully reproduce the hallmarks of human neurolisterisosis will allow addressing the molecular mechanisms underlying Lm ability to induce CNS disease, and improve our understanding of the pathophysiology of this deadly infection.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.