ReviewCellular and molecular life sciences : CMLS2012
The physiological impact of microRNA gene regulation in the retina.
Review in Cellular and molecular life sciences : CMLS, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
35 citing papers in PubMed, 60 citations in OpenAlex.
- Dicer is essential for proper maturation, composition, and function in the postnatal retina.iScience · 2025Article
- Dicer Loss in Müller Glia Leads to a Defined Sequence of Pathological Events Beginning With Cone Dysfunction.Investigative ophthalmology & visual science · 2025Article
- Exploring Early-Stage Retinal Neurodegeneration in Murine Pigmentary Glaucoma: Insights From Gene Networks and miRNA Regulation Analyses.Investigative ophthalmology & visual science · 2023Article
- miRNA Profiling of Developing Rat Retina in the First Three Postnatal Weeks.Cellular and molecular neurobiology · 2023Article
- Therapeutic effects of mesenchymal stem cells-derived extracellular vesicles' miRNAs on retinal regeneration: a review.Stem cell research & therapy · 2021Review
- RNA therapeutics for retinal diseases.Expert opinion on biological therapy · 2021Review
- Analysis of mir-9 Expression Pattern in Rat Retina during Postnatal Development.International journal of molecular sciences · 2021Article
- MicroRNA-18a-5p Administration Suppresses Retinal Neovascularization by Targeting FGF1 and HIF1A.Frontiers in pharmacology · 2020Article
- A Comparative Analysis of Reactive Müller Glia Gene Expression After Light Damage and microRNA-Depleted Müller Glia-Focus on microRNAs.Frontiers in cell and developmental biology · 2020Article
- Effect of let-7a overexpression on the differentiation of conjunctiva mesenchymal stem cells into photoreceptor-like cells.Iranian journal of basic medical sciences · 2019Article
- Down-regulation of microRNA-216a confers protection against yttrium aluminium garnet laser-induced retinal injuryJournal of biosciences · 2018Article
- STAT3-mediated activation ofOncotarget · 2017Article
- Müller glial microRNAs are required for the maintenance of glial homeostasis and retinal architecture.Nature communications · 2017Article
- Functional ectopic neuritogenesis by retinal rod bipolar cells is regulated by miR-125b-5p during retinal remodeling in RCS rats.Scientific reports · 2017Article
- Multimodal Regulation Orchestrates Normal and Complex Disease States in the Retina.Scientific reports · 2017Article
- arrEYE: a customized platform for high-resolution copy number analysis of coding and noncoding regions of known and candidate retinal dystrophy genes and retinal noncoding RNAs.Genetics in medicine : official journal of the American College of Medical Genetics · 2017Article
- An Eye on Age-Related Macular Degeneration: The Role of MicroRNAs in Disease Pathology.Molecular diagnosis & therapy · 2017Review
- MicroRNAs in glaucoma and neurodegenerative diseases.Journal of human genetics · 2017Review
- Retinoids and Retinal Diseases.Annual review of vision science · 2016Review
- Risk factors and biomarkers of age-related macular degeneration.Progress in retinal and eye research · 2016Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
microRNAs (miRNAs) are small, stable RNA molecules that post-transcriptionally regulate gene expression in plants and animals by base pairing to partially complementary sequences on target mRNAs to inhibit protein synthesis. More than 250 miRNAs are reportedly expressed in the retina, and miRNA gene regulation has been shown to affect retinal development, function, and disease. Here we highlight recent advances in understanding the functional roles of vertebrate retinal miRNAs. Details are emerging about the physiological impact of specific miRNAs in the developing and mature retina, and we discuss a group of emerging technologies for studying miRNAs, which can be employed to yield a deeper understanding of retinal miRNA gene regulation.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.