Evidence map›Paper›PMID 22460445›Full record

ReviewFrontiers of medicine2012

Stroke prevention: an update.

Marie-Germaine Bousser

Abstract readReview
PubMed Publisher
In one paragraph

Review in Frontiers of medicine, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
4.6field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 41 citations in OpenAlex.

  1. Article
  2. Rehabilitation in Animal Models of Stroke.Physical therapy research · 2023
    Review
  3. Article
  4. Characteristics of Cerebral Stroke in the Tibet Autonomous Region of China.Medical science monitor : international medical journal of experimental and clinical research · 2020
    Article
  5. Article
  6. Article
  7. Article
  8. Determinants of white matter hyperintensity burden differ at the extremes of ages of ischemic stroke onset.Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association · 2015
    Article
  9. Article
  10. The immune system in stroke: clinical challenges and their translation to experimental research.Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology · 2013
    Review
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Marie-Germaine BousserNeurology Department, Lariboisière Hospital AP-HP, Paris Diderot University, Paris 75010, France. mg.bousser@lrb.aphp.fr
Délégation Paris 7 · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Stroke is a personal, familial, and social disaster. It is the third cause of death worldwide, the first cause of acquired disability, the second cause of dementia, and its cost is astronomic. The burden of stroke is likely to increase given the aging of the population and the growing incidence of many vascular risk factors. Prevention of stroke includes--as for all other diseases--a "mass approach" aiming at decreasing the risk at the society level and an individual approach, aiming at reducing the risk in a given subject. The mass approach is primarily based on the identification and treatment of vascular risk factors and, if possible, in the implementation of protective factors. These measures are the basis of primary prevention but most of them have now been shown to be also effective in secondary prevention. The individual approach combines a vascular risk factor modification and various treatments addressing the specific subtypes of stroke, such as antiplatelet drugs for the prevention of cerebral infarction in large and small artery diseases of the brain, carotid endarterectomy or stenting for tight carotid artery stenosis, and oral anticoagulants for the prevention of cardiac emboli. There is a growing awareness of the huge evidence-to-practice gap that exists in stroke prevention largely due to socio-economic factors. Recent approaches include low cost intervention packages to reduce blood pressure and cheap "polypills" combining in a single tablet aspirin and several drugs to lower blood pressure and cholesterol. Polypill intake should however not lead to abandon the healthy life-style measures which remain the mainstay of stroke prevention.

Indexed as

Atrial FibrillationCarotid StenosisDiabetes ComplicationsEmbolismFibrinolytic AgentsHumansHypercholesterolemiaHypertensionIntracranial ArteriosclerosisLife StyleObesityRisk FactorsSmokingStrokeFibrinolytic Agents

Identifiers

PMID22460445
OpenAlexW1987761487

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.