Evidence map›Paper›PMID 22460021›Full record

ArticleClinical cases in mineral and bone metabolism : the official journal of the Italian Society of Osteoporosis, Mineral Metabolism, and Skeletal Diseases2010

Giant cell tumor in a case of Paget's disease of bone: an aggressive benign tumor exhibiting a quick response to an innovative therapeutic agent.

Roberta Cosso, Vincenzo Nuzzo, Alfonso Zuccoli, Maria Luisa Brandi, Alberto Falchetti

Abstract read
In one paragraph

Article in Clinical cases in mineral and bone metabolism : the official journal of the Italian Society of Osteoporosis, Mineral Metabolism, and Skeletal Diseases, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Diagnosis and Management of Paget's Disease of Bone in Adults: A Clinical Guideline.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2019
    Guideline
  2. Traumatic giant cell tumor of rib: A case report.World journal of clinical cases · 2022
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Roberta CossoCasa di Cura "Villa Erbosa", Bologna, Italy.
Vincenzo Nuzzo
Alfonso Zuccoli
Maria Luisa Brandi
Alberto Falchetti

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Giant cell tumor of bone, also called osteoclastoma, is a rare skeletal complication of Paget's disease of bone. We here report a patient from Southern Italy who developed a GCT infiltrating the neighboring tissues. We will focus on either a review on this rare bone tumor, including some genetic aspects, or the current established therapies. Since this case has been published in International literature, here we report the updated clinical findings on it. Finally, we will describe the therapeutic outcomes of this unique complication of Paget's disease of bone as a rapid response to an innovative therapeutic agent.

Identifiers

PMID22460021
PMCPMC3004463

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.