Evidence map›Paper›PMID 22459798›Full record

ArticleNicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco2012

Dependence on tobacco and nicotine products: a case for product-specific assessment.

Karl Fagerström, Thomas Eissenberg

Open access · greenAbstract read
In one paragraph

Article in Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 62 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
62citing papers in PubMed, 1 pooled it
5.7field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

62 citing papers in PubMed, 1 synthesis or guideline pooled it, 110 citations in OpenAlex.

  1. Overview of Electronic Nicotine Delivery Systems: A Systematic Review.American journal of preventive medicine · 2017
    Pooled it
  2. Trial
  3. Trial
  4. Trial
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  6. Acute effects of snus in never-tobacco users: a pilot study.The American journal of drug and alcohol abuse · 2018
    Trial
  7. Trial
  8. CO exposure and puff topography are associated with Lebanese waterpipe dependence scale score.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2013
    Trial
  9. What is the Addictive Potential from Vaping?Nordisk alkohol- & narkotikatidskrift : NAT · 2026
    Article
  10. Article
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  18. Evaluation of the Psychometric Properties of Dependence Measures for Exclusive Electronic Cigarette Users.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2023
    Article
  19. Article
  20. Article

2 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 2 countries.

Karl FagerströmFagerstrom Consulting AB, Jordkulls Gård 3670, 26878 Kågeröd, Sweden. karl.fagerstrom@swipnet.se
Thomas Eissenberg
Colombian Geological Survey · COVirginia Commonwealth University · US

Funding

Waterpipe tobacco smoke: toxicant exposure and effectsR01CA120142 · NCI · VIRGINIA COMMONWEALTH UNIVERSITY · PI EISSENBERG, THOMAS EVAN · 2008 to 2012
$2.8M
REALTIME waterpipe tobacco smoke toxicant sampling in the natural environmentR01DA025659 · NIDA · VIRGINIA COMMONWEALTH UNIVERSITY · PI EISSENBERG, THOMAS EVAN, SHIHADEH, ALAN · 2011 to 2015
$1.8M
NCI NIH HHS CA120142NIDA NIH HHS DA025659
6 · The paper itself

Abstract

The International Classification of Diseases and the Diagnostic and Statistical Manual for diagnosing tobacco/nicotine dependence emphasize the dependence-producing drug nicotine. These diagnostic tools have been challenged on grounds of poor predictive validity, and they do not differentiate across various forms of nicotine-containing products. In fact, nicotine-containing products (e.g., tobacco cigarettes, smokeless tobacco [ST], waterpipe, electronic cigarettes [ECIGs], and nicotine replacement [NR] products) have very different characteristics both in terms of sensory and behavioral involvement and also in pharmacokinetic and pharmacodynamic effects. For example, a cigarette and a nicotine patch are very different on almost every one of these dimensions. When ability to stop using a nicotine/tobacco product is used as a criterion for dependence, success rates vary considerably across products: Tobacco cigarette cessation is more difficult than ST cessation that in turn is more difficult than NR product cessation. Based on these results, we hypothesize that there is a continuum of dependence as much as there is a continuum of harm, with tobacco cigarettes and NR products on opposite ends of both continua and other products (waterpipe and ECIGs) somewhere in between. In order to capture more precisely the dependence produced by both nicotine and its administration forms, product-specific instruments may be required. The pros and cons of this approach are discussed.

Indexed as

Tobacco Use DisorderHumansNicotineSelf AdministrationTobacco ProductsTobacco, SmokelessNicotine

Identifiers

PMID22459798
PMCPMC3611984
OpenAlexW2146978276

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.