ReviewCurrent opinion in neurobiology2012
Signaling in dendritic spines and spine microdomains.
Review in Current opinion in neurobiology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
40 citing papers in PubMed.
- The Polyadenosine RNA-Binding Protein ZC3H14 Localizes to Synapses and Regulates Synaptosomal CaMKIIα Levels.bioRxiv : the preprint server for biology · 2026Article
- Kinetochore proteins control microtubule dynamics in postmitotic neurons to regulate the formation of dendritic spines.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Deep mapping of thebioRxiv : the preprint server for biology · 2025Article
- Assessing protein distribution and dendritic spine morphology relationships using structured illumination microscopy in cultured neurons.STAR protocols · 2024Article
- Fast and slow: Recording neuromodulator dynamics across both transient and chronic time scales.Science advances · 2024Article
- Trafficking proteins show limited differences in mobility across different postsynaptic spines.iScience · 2023Article
- Morphological Features of Human Dendritic Spines.Advances in neurobiology · 2023Review
- Introduction: What Are Dendritic Spines?Advances in neurobiology · 2023Article
- Long-term potentiation in neurogliaform interneurons modulates excitation-inhibition balance in the temporoammonic pathway.The Journal of physiology · 2022Article
- IRSp53 promotes postsynaptic density formation and actin filament bundling.The Journal of cell biology · 2022Article
- Unraveling Brain Microcircuits, Dendritic Spines, and Synaptic Processing Using Multiple Complementary Approaches.Frontiers in physiology · 2022Article
- The role of molecular diffusion within dendritic spines in synaptic function.The Journal of general physiology · 2021Review
- The Subcortical-Allocortical- NeocorticalFrontiers in synaptic neuroscience · 2021Article
- The Kinase Specificity of Protein Kinase Inhibitor Peptide.Frontiers in pharmacology · 2021Article
- Dendritic spine density is increased on nucleus accumbens D2 neurons after chronic social defeat.Scientific reports · 2020Article
- The Nebulin Family LIM and SH3 Proteins Regulate Postsynaptic Development and Function.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2020Article
- Changes in Dendritic Spine Density and Inhibitory Perisomatic Connectivity onto Medium Spiny Neurons in L-Dopa-Induced Dyskinesia.Molecular neurobiology · 2019Article
- Neuronal sub-compartmentalization: a strategy to optimize neuronal function.Biological reviews of the Cambridge Philosophical Society · 2019Review
- Review
- Oligodendrocyte- and Neuron-Specific Nogo-A Restrict Dendritic Branching and Spine Density in the Adult Mouse Motor Cortex.Cerebral cortex (New York, N.Y. : 1991) · 2018Article
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
The specialized morphology of dendritic spines creates an isolated compartment that allows for localized biochemical signaling. Recent studies have revealed complexity in the function of the spine head as a signaling domain and indicate that (1) the spine is functionally subdivided into multiple independent microdomains and (2) not all biochemical signals are equally compartmentalized within the spine. Here we review these findings as well as the developments in fluorescence microscopy that are making possible direct monitoring of signaling within spines and, in the future, within sub-spine microdomains.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.