Evidence map›Paper›PMID 22459515›Full record

ReviewTrends in biotechnology2012

Perspectives on cell reprogramming with RNA.

Jai-Yoon Sul, Tae Kyung Kim, Jae Hee Lee, James Eberwine

Abstract readReview
In one paragraph

Review in Trends in biotechnology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Frontiers in cellular neuroscience · 2021
    Article
  3. Article
  4. Article
  5. Determinants of expression variability.Nucleic acids research · 2014
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jai-Yoon SulDepartment of Pharmacology, University of Pennsylvania Perelman School of Medicine, John Morgan Building, Room 37, 36th and Hamilton Walk, Philadelphia, PA 19104, USA.
Tae Kyung Kim
Jae Hee Lee
James Eberwine

Funding

Cellular logic of phenotypeDP1OD004117 · OD · UNIVERSITY OF PENNSYLVANIA · PI EBERWINE, JAMES H · 2008 to 2011
$3.1M
Cellular logic of phenotypeDP1MH099902 · NIMH · UNIVERSITY OF PENNSYLVANIA · PI EBERWINE, JAMES H · 2012 to 2012
$780k
INCREASING BREAST AND CERVICAL CANCER SCREENING RATES IN LO-INCOME, RURAL, HISPANU58DP004117 · DP · NEBRASKA ST DEPT OF HEALTH & HUMAN SERVS · PI LEYPOLDT, MELISSA D · 2012 to 2012
$195k
NCCDPHP CDC HHS DP004117NCCDPHP CDC HHS U58 DP004117NIH HHS DP1 OD004117NIMH NIH HHS DP1 MH099902
6 · The paper itself

Abstract

Recent advances in cell reprogramming have permitted the development of different stem cell lines and specific differentiated cell types using distinct technologies. Cell reprogramming is largely mediated by DNA and RNA. In this review, we explore the RNA-mediated cell reprogramming to induce specific target cell generation including stem cells, brain cells and cardiac cells. The ability of RNA populations to produce direct cell to cell phenotypic conversion is called Transcriptome Induced PhenotypeRemodeling (TIPeR). The theory and utility of RNA use for cellular reprogramming is explored in this review.

Indexed as

Cell DifferentiationCell Physiological PhenomenaGene Expression RegulationAnimalsDNAHumansRNADNARNA

Identifiers

PMID22459515
PMCPMC3335965

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.