ReviewCurrent opinion in cell biology2012
Revisiting higher-order and large-scale chromatin organization.
Review in Current opinion in cell biology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
30 citing papers in PubMed, 64 citations in OpenAlex.
- Chromatin Liquid-Liquid Phase Separation (LLPS) Is Regulated by Ionic Conditions and Fiber Length.Cells · 2022Article
- A reappraisal of the form - function problem. Theory and phenomenology.Theory in biosciences = Theorie in den Biowissenschaften · 2022Article
- Changes in chromatin accessibility landscape and histone H3 core acetylation during valproic acid-induced differentiation of embryonic stem cells.Epigenetics & chromatin · 2021Article
- Physical Nature of Chromatin in the Nucleus.Cold Spring Harbor perspectives in biology · 2021Review
- In situ nuclear DNA methylation in dilated cardiomyopathy: an endomyocardial biopsy study.ESC heart failure · 2020Article
- Processive DNA synthesis is associated with localized decompaction of constitutive heterochromatin at the sites of DNA replication and repair.Nucleus (Austin, Tex.) · 2019Article
- Bridging the dynamics and organization of chromatin domains by mathematical modeling.Nucleus (Austin, Tex.) · 2017Article
- Three-dimensional positioning and structure of chromosomes in a human prophase nucleus.Science advances · 2017Article
- Nucleosome-nucleosome interactions via histone tails and linker DNA regulate nuclear rigidity.Molecular biology of the cell · 2017Article
- Atomic force microscopy of chromatin arrays reveal non-monotonic salt dependence of array compaction in solution.PloS one · 2017Article
- Binding of DNA-bending non-histone proteins destabilizes regular 30-nm chromatin structure.PLoS computational biology · 2017Article
- Chromatin structure-dependent conformations of the H1 CTD.Nucleic acids research · 2016Article
- 4D Visualization of replication foci in mammalian cells corresponding to individual replicons.Nature communications · 2016Article
- Coming to terms with chromatin structure.Chromosoma · 2016Review
- Structural organization of very small chromosomes: study on a single-celled evolutionary distant eukaryote Giardia intestinalis.Chromosoma · 2015Article
- Article
- Chromatin as dynamic 10-nm fibers.Chromosoma · 2014Review
- Chromatin without the 30-nm fiber: constrained disorder instead of hierarchical folding.Epigenetics · 2014Review
- Histone variants: the tricksters of the chromatin world.Current opinion in genetics & development · 2014Review
- Large-scale chromatin organization: the good, the surprising, and the still perplexing.Current opinion in cell biology · 2014Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
The past several years has seen increasing appreciation for plasticity of higher-level chromatin folding. Four distinct '30nm' chromatin fiber structures have been identified, while new in situ imaging approaches have questioned the universality of 30nm chromatin fibers as building blocks for chromosome folding in vivo. 3C-based approaches have provided a non-microscopic, genomic approach to investigating chromosome folding while uncovering a plethora of long-distance cis interactions difficult to accommodate in traditional hierarchical chromatin folding models. Recent microscopy based studies have suggested complex topologies co-existing within linear interphase chromosome structures. These results call for a reappraisal of traditional models of higher-level chromatin folding.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.