ArticleChemical senses2012
Cluster analysis of rat olfactory bulb responses to diverse odorants.
Article in Chemical senses, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
5 citing papers in PubMed.
- An Ensemble Learning Method for Robot Electronic Nose with Active Perception.Sensors (Basel, Switzerland) · 2021Article
- Interaction between age and perceptual similarity in olfactory discrimination learning in F344 rats: relationships with spatial learning.Neurobiology of aging · 2017Article
- In vivo identification of eugenol-responsive and muscone-responsive mouse odorant receptors.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2014Article
- Characterizing olfactory perceptual similarity using carbon chain discrimination in Fischer 344 rats.Chemical senses · 2014Article
- Keeping their distance? Odor response patterns along the concentration range.Frontiers in systems neuroscience · 2012Article
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
In an effort to deepen our understanding of mammalian olfactory coding, we have used an objective method to analyze a large set of odorant-evoked activity maps collected systematically across the rat olfactory bulb to determine whether such an approach could identify specific glomerular regions that are activated by related odorants. To that end, we combined fuzzy c-means clustering methods with a novel validity approach based on cluster stability to evaluate the significance of the fuzzy partitions on a data set of glomerular layer responses to a large diverse group of odorants. Our results confirm the existence of glomerular response clusters to similar odorants. They further indicate a partial hierarchical chemotopic organization wherein larger glomerular regions can be subdivided into smaller areas that are rather specific in their responses to particular functional groups of odorants. These clusters bear many similarities to, as well as some differences from, response domains previously proposed for the glomerular layer of the bulb. These data also provide additional support for the concept of an identity code in the mammalian olfactory system.
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Registered trials
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