Evidence map›Paper›PMID 22458987›Full record

Trial reportPsychosomatics

Depressive symptom deterioration among predominantly Hispanic diabetes patients in safety net care.

Kathleen Ell, Wayne Katon, Pey-Jiuan Lee, Suad Kapetanovic, Jeffrey Guterman, Bin Xie, Chih-Ping Chou

Open access · greenAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Psychosomatics. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 3 pooled it
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 3 syntheses or guidelines pooled it, 19 citations in OpenAlex.

  1. Collaborative care approaches for people with severe mental illness.The Cochrane database of systematic reviews · 2024
    Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 1 country.

Kathleen EllSchool of Social Work, University of Southern California, Los Angeles 90089-0411, USA. ell@usc.edu
Wayne Katon
Pey-Jiuan Lee
Suad Kapetanovic
Jeffrey Guterman
Bin Xie
Chih-Ping Chou
University of Southern California · USClaremont Graduate University · USLos Angeles County Department of Health Services · USNational Institutes of Health · USUniversity of Washington · US

Funding

Southern California Clinical and Translational Science InstituteUL1TR000130 · NCATS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI BUCHANAN, THOMAS A · 2012 to 2015
$36.0M
Multifaceted Depression Diabetes Program for HispanicsR01MH068468 · NIMH · UNIVERSITY OF SOUTHERN CALIFORNIA · PI ELL, KATHLEEN R · 2005 to 2008
$3.1M
Quality Improvement of School Mental Health ServicesK08MH069741 · NIMH · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI KATAOKA, SHERYL H · 2004 to 2008
$769k
NCATS NIH HHS UL1 TR000130NIMH NIH HHS K08 MH069741NIMH NIH HHS K-24 MH069741NIMH NIH HHS R01 MH068468
6 · The paper itself

Abstract

objectiveThis study examines clinical predictors of symptom deterioration (relapse/recurrence) at the completion of a clinical intervention trial of depressed, low-income, predominantly Hispanic diabetes patients who were randomized to socio-culturally adapted collaborative depression treatment or usual care and who no longer met clinically significant depression criteria at 12 months post-trial baseline.

methodsA sub-cohort of 193 diabetes patients with major depression symptoms at baseline, who were randomized to a 12-month collaborative care intervention (INT) (problem-solving therapy and/or pharmacotherapy, telephone symptom monitoring/relapse prevention, behavioral activation and patient navigation support) or enhanced usual care (EUC), and who did not meet major depression criteria at 12 months were subsequently observed over 18 to 24 months.

resultsPost-trial depression symptom deterioration was similar between INT (35.2%) and EUC (35.3%) groups. Among the combined groups, significant predictors of symptom deterioration were baseline history of previous depression and/or dysthymia (odds ratio [OR] = 2.66), 12-month PHQ-9 score (OR = 1.22), antidepressant treatment receipt during the initial 12-months (OR = 2.38), 12-month diabetes symptoms (OR = 2.27), and new ICD-9 medical diagnoses in the initial 12 months (OR = 1.11) (R2 = 27%; max-rescaled R2 = 37%; likelihood ratio test, χ2 = 59.79, df = 5, P < 0.0001).

conclusionsAmong predominantly Hispanic diabetes patients in community safety net primary care clinics whose depression had improved over 1 year, more than one-third experienced symptom deterioration over the following year. A primary care management depression care protocol that includes ongoing depression symptom monitoring, antidepressant adherence, and diabetes and co-morbid illness monitoring plus depression medication adjustment and behavioral activation may reduce and/or effectively treat depression symptom deterioration.

Indexed as

Health StatusAntidepressive AgentsCommunity Health ServicesComorbidityCooperative BehaviorDepressionDiabetes Mellitus, Type 2FemaleHispanic or LatinoHumansLogistic ModelsLos AngelesMajor Depressive DisorderMaleMiddle AgedPatient ComplianceAntidepressive Agents

Identifiers

PMID22458987
PMCPMC3389136
OpenAlexW2032413621

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.