Evidence map›Paper›PMID 22458466›Full record

ArticleThe Journal of law, medicine & ethics : a journal of the American Society of Law, Medicine & Ethics2012

Conflicts among multinational ethical and scientific standards for clinical trials of therapeutic interventions.

Jacob M Kolman, Nelda P Wray, Carol M Ashton, Danielle M Wenner, Anna F Jarman, Baruch A Brody

Abstract read
In one paragraph

Article in The Journal of law, medicine & ethics : a journal of the American Society of Law, Medicine & Ethics, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jacob M KolmanBaylor College of Medicine Center for Medical Ethics and Health Policy, Houston Texas, USA.
Nelda P Wray
Carol M Ashton
Danielle M Wenner
Anna F Jarman
Baruch A Brody

Funding

Ethical & Methodological Standards for Trials of Invasive Therapeutic ProceduresR01CA134995 · NCI · METHODIST HOSPITAL RESEARCH INSTITUTE · PI ASHTON, CAROL M · 2008 to 2010
$1.9M
NCI NIH HHS R01 CA134995
6 · The paper itself

Abstract

Utilizing a sorted compendium of international clinical trial standards, investigators identified 15 conflicts among ethical and methodological guidance. Analysis distinguishes interpretational issues, lack of clarity, and contradiction as factors to be addressed if international trial guidance is to be improved.

Indexed as

InternationalityClinical Trials as TopicHumansPatient SelectionTherapies, Investigational

Identifiers

PMID22458466
PMCPMC3567849

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.