Evidence map›Paper›PMID 22458375›Full record

ArticleDisability and rehabilitation2012

A pilot study of the effects of internet-based cognitive stimulation on neuropsychological function in HIV disease.

James T Becker, Mary Amanda Dew, Howard J Aizenstein, Oscar L Lopez, Lisa Morrow, Judith Saxton, Lluís Tárraga

Registry-linked trialAbstract readEvaluation Study
In one paragraph

Article in Disability and rehabilitation, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05571761 (Feasibility and Usefulness of a Neuropsychological Telerehabilitation Program in Asymptomatic HIV Patients), which is not on this map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05571761 nawithdrawnnot on this mapstarted 2022, after this paper: background citation

Feasibility and Usefulness of a Neuropsychological Telerehabilitation Program in Asymptomatic HIV Patients: Pilot Randomized Controlled Trial

TypeinterventionalSponsorUniversidad Nacional Autonoma de MexicoRan2022 to 2024Enrolled0ConditionsTelerehabilitation, Neuropsychology, HIV DementiaArmsCognitive stimulation program
3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 35 citations in OpenAlex.

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  14. A Flexible and Integrated System for the Remote Acquisition of Neuropsychological Data in Stroke Research.Telemedicine journal and e-health : the official journal of the American Telemedicine Association · 2016
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

James T BeckerDepartment of Psychiatry, University of Pittsburgh, Pittsburgh, PA, USA. beckerjt@pitt.edu
Mary Amanda Dew
Howard J Aizenstein
Oscar L Lopez
Lisa Morrow
Judith Saxton
Lluís Tárraga
University of Pittsburgh · USFundació ACE · ESNeurology, Inc · US

Funding

University of Pittsburgh Multicenter AIDS Cohort Study (MACS)U01AI035041 · NIAID · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI MARTINSON, JEREMY JAMES, RINALDO, CHARLES R · 1993 to 2018
$71.4M
TREATMENT OF DEPRESSION IN ALZHEIMER'S DISEASEP50AG005133 · NIA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI BECKER, JAMES T. · 1985 to 2019
$43.0M
Pilot Study of an Internet-based Cognitive Stimulation Program in AIDSR03MH081723 · NIMH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI BECKER, JAMES T. · 2007 to 2008
$149k
NIAID NIH HHS AI35041NIAID NIH HHS U01 AI035041NIA NIH HHS AG05133NIA NIH HHS P50 AG005133NIMH NIH HHS MH081723NIMH NIH HHS R03 MH081723
6 · The paper itself

Abstract

purposeMild cognitive deficits associated with HIV disease can affect activities of daily living, so interventions that reduce them may have a long-term effect on quality of life. We evaluated the feasibility of a cognitive stimulation program (CSP) to improve neuropsychological test performance in HIV disease.

methodsSixty volunteers (30 HIV-infected) participated. The primary outcome was the change in neuropsychological test performance as indexed by the Global Impairment Rating; secondary outcomes included mood (Brief Symptom Inventory subscales) and quality of life rating (Medical Outcomes Survey-HIV) scales.

resultsFifty-two participants completed all 24 weeks of the study, and 54% of the participants in the CSP group successfully used the system via internet access from their home or other location. There was a significant interaction between usage and study visit such that the participants who used the program most frequently showed significantly greater improvements in cognitive functioning (F(3, 46.4 = 3.26, p = 0.030); none of the secondary outcomes were affected by the dose of CSP.

conclusionsWe found it possible to complete an internet-based CSP in HIV-infected individuals; ease of internet access was a key component for success. Participants who used the program most showed improvements in cognitive function over the 24-week period, suggesting that a larger clinical trial of CSP may be warranted.

Indexed as

InternetActivities of Daily LivingAdultAgedCase-Control StudiesCognitive Behavioral TherapyCognitive DysfunctionFeasibility StudiesFemaleFollow-Up StudiesHIV InfectionsHumansMaleMiddle AgedNeuropsychological TestsPilot Projects

Identifiers

PMID22458375
PMCPMC3394884
OpenAlexW2045772924

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.