ArticleArchives of medical science : AMS2012
Reduction in atherosclerotic events: a retrospective study in an outpatient cardiology practice.
Article in Archives of medical science : AMS, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 15 citations in OpenAlex.
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- Treatment of non-ST-elevation myocardial infarction and ST-elevation myocardial infarction in patients with chronic kidney disease.Archives of medical science : AMS · 2013Article
- Blood pressure levels and stroke: J-curve phenomenon?Current hypertension reports · 2013Review
- Persistence with statin therapy in Hungary.Archives of medical science : AMS · 2013Article
- Pregnancy-associated plasma protein A predicts adverse vascular events in patients with coronary heart disease: a systematic review and meta-analysis.Archives of medical science : AMS · 2013Article
- Contrast imaging and gene delivery through the combined use of novel cationic liposomal microbubbles and ultrasound in rat carotid arteries.Archives of medical science : AMS · 2013Article
- Risk factor reduction in progression of angiographic coronary artery disease.Archives of medical science : AMS · 2012Article
- The clinical benefit of implementing guidelines in cardiovascular disease prevention in real world settings.Archives of medical science : AMS · 2012Article
- The impact of statin therapy on long-term cardiovascular outcomes in an outpatient cardiology practice.Archives of medical science : AMS · 2012Article
- Editorial on management of diabetes mellitus with coronary artery disease.Archives of medical science : AMS · 2011Article
- The impact of statin therapy on long-term cardiovascular outcomes in an outpatient cardiology practice.Medical science monitor : international medical journal of experimental and clinical research · 2011Article
Corrections and comments
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Authors and funding
9 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionAlthough atherosclerotic disease cannot be cured, risk of recurrent events can be reduced by application of evidence-based treatment protocols involving aspirin, beta blockers, angiotensin-converting enzyme inhibitors or angiotensin receptor blockers, and statin medications. We studied atherosclerotic event rates in a patient population treated before and after the development of aggressive risk factor reduction treatment protocols. MATERIAL AND
methodsWe performed a retrospective chart review of patients presenting for follow-up treatment of coronary artery disease in a community cardiology practice, comparing atherosclerotic event rates and medication usage in a 2-year treatment period prior to 2002 and a 2-year period in 2005-2008. Care was provided in both the early and later eras by 7 board-certified cardiologists in a suburban cardiology practice. Medication usage was compared in both treatment eras. The primary outcome was a composite event rate of myocardial infarction, cerebrovascular events, and coronary interventions.
resultsThree hundred and fifty-seven patients were studied, with a follow-up duration of 12.1 (±3.5) years. There were 132 composite events in 104 patients (29.1%) in the early era compared to 40 events in 33 patients (9.2%) in the later era (p < 0.0001). From the early to the later eras, there was an increase in use of β-blockers (66% to 83%, p < 0.0001), angiotensin-converting enzyme inhibitors or angiotensin receptor blockers (34% to 80%, p < 0.0001), and statins (40% to 90%, p < 0.0001).
conclusionsApplication of aggressive evidence-based medication protocols for treatment of atherosclerosis is associated with a significant decrease in atherosclerotic events or need for coronary intervention.
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