ArticleArchives of medical science : AMS2012
The impact of statin therapy on long-term cardiovascular outcomes in an outpatient cardiology practice.
Article in Archives of medical science : AMS, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed, 15 citations in OpenAlex.
- Infusional high-density lipoproteins therapies as a novel strategy for treating atherosclerosis.Archives of medical science : AMS · 2017Article
- Lipid-lowering therapy in older persons.Archives of medical science : AMS · 2015Article
- Lipid, blood pressure and kidney update 2013.International urology and nephrology · 2014Review
- Statin treatment in the elderly: how much do we know?Archives of medical science : AMS · 2013Article
- Persistence with statin therapy in Hungary.Archives of medical science : AMS · 2013Article
- Association between heart rate at rest and myocardial perfusion in patients with acute myocardial infarction undergoing cardiac rehabilitation - a pilot study.Archives of medical science : AMS · 2012Article
- The clinical benefit of implementing guidelines in cardiovascular disease prevention in real world settings.Archives of medical science : AMS · 2012Article
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Authors and funding
9 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionStatins reduce coronary events in patients with coronary artery disease. MATERIAL AND
methodsChart reviews were performed in 305 patients (217 men and 88 women, mean age 74 years) not treated with statins during the first year of being seen in an outpatient cardiology practice but subsequently treated with statins. Based on the starting date of statins use, the long-term outcomes of myocardial infarction (MI), percutaneous coronary intervention (PCI), and coronary artery bypass graft surgery (CABGs) before and after statin use were compared.
resultsMean follow-up was 65 months before statins use and 66 months after statins use. Myocardial infarction occurred in 31 of 305 patients (10%) before statins, and in 13 of 305 patients (4%) after statins (p < 0.01). Percutaneous coronary intervention had been performed in 66 of 305 patients (22%) before statins and was performed in 41 of 305 patients (13%) after statins (p < 0.01). Coronary artery bypass graft surgery had been performed in 56 of 305 patients (18%) before statins and in 20 of 305 patients (7%) after statins (p < 0.001). Stepwise logistic regression showed statins use was an independent risk factor for MI (odds ratio = 0.0207, 95% CI, 0.0082-0.0522, p < 0.0001), PCI (odds ratio = 0.0109, 95% CI, 0.0038-0.0315, p < 0.0001) and CABGs (odds ratio = 0.0177, 95% CI = 0.0072-0.0431, p < 0.0001)
conclusionsStatins use in an outpatient cardiology practice reduces the incidence of MI, PCI, and CABGs.
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