Evidence map›Paper›PMID 22457286›Full record

ArticleThe Journal of infectious diseases2012

Opportunities and challenges for cost-efficient implementation of new point-of-care diagnostics for HIV and tuberculosis.

Marco Schito, Trevor F Peter, Sean Cavanaugh, Amy S Piatek, Gloria J Young, Heather Alexander, William Coggin, Gonzalo J Domingo, Dennis Ellenberger, Eugen Ermantraut and 5 more

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of infectious diseases, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
55citing papers in PubMed, 1 pooled it
4.8field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

55 citing papers in PubMed, 1 synthesis or guideline pooled it, 119 citations in OpenAlex.

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  19. Frugal Science Powered by Curiosity.Industrial & engineering chemistry research · 2021
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 13 institutions in 6 countries.

Marco SchitoDivision of AIDS, Henry M. Jackson Foundation for Advancement of Military Medicine, National Institutes of Health, Bethesda, Maryland 20892-7628, USA. schitom@niaid.nih.gov
Trevor F Peter
Sean Cavanaugh
Amy S Piatek
Gloria J Young
Heather Alexander
William Coggin
Gonzalo J Domingo
Dennis Ellenberger
Eugen Ermantraut
Ilesh V Jani
Achilles Katamba
Kara M Palamountain
Shaffiq Essajee
David W Dowdy
Centers for Disease Control and Prevention · USAIDS United · USAlere (Germany) · DEBecton Dickinson (United States) · USClinton Health Access Initiative · USJohns Hopkins University · USMakerere University · UGNational Directorate of Geology · MZNational Institutes of Health · USNorthwestern University · USProgram for Appropriate Technology in Health · USUnited States Agency for International Development · USWorld Health Organization · CH

Funding

NIAID NIH HHS HHSN272200800014C
6 · The paper itself

Abstract

Stakeholders agree that supporting high-quality diagnostics is essential if we are to continue to make strides in the fight against human immunodeficiency virus (HIV) and tuberculosis. Despite the need to strengthen existing laboratory infrastructure, which includes expanding and developing new laboratories, there are clear diagnostic needs where conventional laboratory support is insufficient. Regarding HIV, rapid point-of-care (POC) testing for initial HIV diagnosis has been successful, but several needs remain. For tuberculosis, several new diagnostic tests have recently been endorsed by the World Health Organization, but a POC test remains elusive. Human immunodeficiency virus and tuberculosis are coendemic in many high prevalence locations, making parallel diagnosis of these conditions an important consideration. Despite its clear advantages, POC testing has important limitations, and laboratory-based testing will continue to be an important component of future diagnostic networks. Ideally, a strategic deployment plan should be used to define where and how POC technologies can be most efficiently and cost effectively integrated into diagnostic algorithms and existing test networks prior to widespread scale-up. In this fashion, the global community can best harness the tremendous capacity of novel diagnostics in fighting these 2 scourges.

Indexed as

Bacteriological TechniquesHIV InfectionsHumansLaboratoriesPoint-of-Care SystemsQuality Assurance, Health CareTuberculosisVirology

Identifiers

PMID22457286
PMCPMC3334507
OpenAlexW2165845866

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.