Trial reportPsychopharmacology2012
The effects of energy drink in combination with alcohol on performance and subjective awareness.
Trial report in Psychopharmacology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Alcohol mixed with energy drink (AMED): A critical review and meta-analysis.Human psychopharmacology · 2018Pooled it
- Effects of Mixing Energy Drinks With Alcohol on Driving-Related Skills.The international journal of neuropsychopharmacology · 2022Trial
- Trial
- Alcohol and energy drink use among adolescents seeking emergency department care.Addictive behaviors · 2015Trial
- Effects of alcohol mixed with energy drink and alcohol alone on subjective intoxication.Amino acids · 2013Trial
- Effects of caffeine and alcohol on mood and performance changes following consumption of lager.Psychopharmacology · 2013Trial
- No significant gender differences in driving-related skills following alcohol mixed with energy drinks during an experimental binge-drinking episode.Frontiers in pharmacology · 2025Article
- An on-premise study to investigate the effects of mixing alcohol with caffeinated beverages.Brain and behavior · 2022Article
- The Effects of Alcohol Hangover on Mood and Performance Assessed at Home.Journal of clinical medicine · 2020Article
- Energy drinks mixed with alcohol: are there any risks?Nutrition reviews · 2015Article
- Cardiovascular complications from consumption of high energy drinks: recent evidence.Journal of human hypertension · 2015Review
- Energy drinks mixed with alcohol: what are the risks?Nutrition reviews · 2014Review
- "Wired," yet intoxicated: modeling binge caffeine and alcohol co-consumption in the mouse.Alcoholism, clinical and experimental research · 2014Article
- Energy drink consumption and associated health behaviors among university students in an urban setting.Journal of community health · 2014Article
- Impulsivity and alcohol demand in relation to combined alcohol and caffeine use.Experimental and clinical psychopharmacology · 2013Article
- Conditioned reinforcement and locomotor activating effects of caffeine and ethanol combinations in mice.Pharmacology, biochemistry, and behavior · 2013Article
- Caffeinated Alcoholic Beverages - An Emerging Trend in Alcohol Abuse.Journal of addiction research & therapy · 2013Article
- The combined effects of alcohol, caffeine, and expectancies on subjective experience, impulsivity, and risk-taking.Experimental and clinical psychopharmacology · 2013Article
- The alcohol mixed with energy drink debate: masking the facts! A commentary on "Mixing an energy drink with an alcoholic beverage increases motivation for more alcohol in college students" by Marczinski and colleagues (in press).Alcoholism, clinical and experimental research · 2013Article
- Alcohol mixed energy drink usage and risk-taking among college students in Western New York State.Journal of American college health : J of ACHArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
rationaleThis study investigated the coadministration of an energy drink with alcohol to study the effects on subjective intoxication and objective performance.
objectivesThis study aims to evaluate the objective and subjective effects of alcohol versus placebo at two alcohol doses, alone and in combination with an energy drink, in a balanced order, placebo-controlled, double-blind design.
methodsTwo groups of ten healthy volunteers, mean (SD) age of 24 (6.5), participated in the study. One group consumed energy drink containing 80 mg of caffeine and the other consumed a placebo drink, with both receiving two alcohol doses (0.046 and 0.087% breathalyser alcohol concentration). Tests included breath alcohol assessment, objective measures of performance (reaction time, word memory and Stroop task) and subjective visual analogue mood scales.
resultsParticipants showed significantly impaired reaction time and memory after alcohol compared to the no alcohol condition and had poorer memory after the higher alcohol dose. Stroop performance was improved with the energy drink plus alcohol combination compared to the placebo drink plus alcohol combination. Participants felt significant subjective dose-related impairment after alcohol compared to no alcohol. Neither breath alcohol concentration nor the subjective measures showed a significant difference between the energy drink and the placebo energy drink when combined with alcohol.
conclusionsSubjective effects reflected awareness of alcohol intoxication and sensitivity to increasing alcohol dose. There were no overall significant group differences for subjective measures between energy drink and placebo groups in the presence of alcohol and no evidence that the energy drink masked the subjective effects of alcohol at either dose.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.