Trial reportJournal of autism and developmental disorders2012
Are prenatal ultrasound scans associated with the autism phenotype? Follow-up of a randomised controlled trial.
Trial report in Journal of autism and developmental disorders, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
10 citing papers in PubMed, 2 syntheses or guidelines pooled it, 24 citations in OpenAlex.
- Routine ultrasound in late pregnancy (after 24 weeks' gestation).The Cochrane database of systematic reviews · 2015Pooled it
- Fetal and umbilical Doppler ultrasound in normal pregnancy.The Cochrane database of systematic reviews · 2015Pooled it
- Prenatal ultrasound use and risk of autism spectrum disorder: Findings from the case-control Study to Explore Early Development.Paediatric and perinatal epidemiology · 2023Article
- A prospective study of fetal head growth, autistic traits and autism spectrum disorder.Autism research : official journal of the International Society for Autism Research · 2018Article
- A Relationship Between Early Language Skills and Adult Autistic-Like Traits: Evidence from a Longitudinal Population-Based Study.Journal of autism and developmental disorders · 2017Article
- Severity of ASD symptoms and their correlation with the presence of copy number variations and exposure to first trimester ultrasound.Autism research : official journal of the International Society for Autism Research · 2017Article
- Environmental factors associated with autism spectrum disorder: a scoping review for the years 2003-2013.Health promotion and chronic disease prevention in Canada : research, policy and practice · 2017Article
- Ultrasound and Autism Spectrum Disorder.Australasian journal of ultrasound in medicine · 2016Article
- Mice exposed to diagnostic ultrasound in utero are less social and more active in social situations relative to controls.Autism research : official journal of the International Society for Autism Research · 2014Article
- A New Methodology of Viewing Extra-Axial Fluid and Cortical Abnormalities in Children with Autism via Transcranial Ultrasonography.Frontiers in human neuroscience · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
An existing randomised controlled trial was used to investigate whether multiple ultrasound scans may be associated with the autism phenotype. From 2,834 single pregnancies, 1,415 were selected at random to receive ultrasound imaging and continuous wave Doppler flow studies at five points throughout pregnancy (Intensive) and 1,419 to receive a single imaging scan at 18 weeks (Regular), with further scans only as indicated on clinical grounds. There was no significant difference in the rate of Autism Spectrum Disorder between the Regular (9/1,125, 0.8 %) and Intensive (7/1,167, 0.6 %) groups, nor a difference between groups in the level of autistic-like traits in early adulthood. There is no clear link between the frequency and timing of prenatal ultrasound scans and the autism phenotype.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.