Evidence map›Paper›PMID 22456786›Full record

ArticleThe journal of nutrition, health & aging2012

Vitamin B12 deficiency in Australian residential aged care facilities.

C Mirkazemi, G M Peterson, P C Tenni, S L Jackson

Open access · greenAbstract read
In one paragraph

Article in The journal of nutrition, health & aging, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 32 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Risk of dementia in elderly patients with the use of proton pump inhibitors.European archives of psychiatry and clinical neuroscience · 2015
    Article
  10. [Vitamin B12 deficiency in the elderly].Zeitschrift fur Gerontologie und Geriatrie · 2015
    Article
  11. Cardioprotective role of vitamin D receptor in circulating endothelial cells of ApoE-deficient mice.International journal of clinical and experimental medicine · 2015
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

C MirkazemiUnit for Medication Outcomes Research and Education, School of Pharmacy, University of Tasmania, Hobart, Tasmania 7001, Australia.
G M Peterson
P C Tenni
S L Jackson
University of Tasmania · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo determine the prevalence of undiagnosed vitamin B12 deficiency among residential aged care facility residents in southern Tasmania, Australia, and to identify associated risk factors. DESIGN AND

settingCross-sectional study of residents from five southern Tasmanian residential aged care facilities.

participantsTwo hundred and fifty-nine residents without a prior diagnosis of vitamin B12 deficiency or recorded serum B12 level within the past 6 months were approached to have their serum B12 level tested. One hundred and sixty (61%) residents consented and their doctors were contacted for further consent. A total of 130 (50%) residents completed the study. MEASUREMENTS: Clinical and demographic characteristics, and serum B12 level.

resultsOf the 130 residents tested, 18 residents (14%) were considered vitamin B12 deficient (serum level <150 pmol/L), 47 (36%) were equivocal (150 pmol/L to 250 pmol/L) and 65 (50%) had normal serum B12 levels (>250 pmol/L). There was a weak negative correlation between age and serum B12 level in those residents not taking a multivitamin (n=120, r=-0.19, p<0.05). The use of a multivitamin or antipsychotic drug were associated with altered mean serum B12 levels (+137 pmol/L, p<0.001 and -70 pmol/L, p<0.001 respectively).

conclusionAs vitamin B12 deficiency can manifest in a range of symptoms that are frequently misdiagnosed, the finding of undetected deficiency in 14% of residents is a cause for concern. Oral multivitamin supplementation may help prevent deficiency, and potentially treat existing deficiencies in older institutionalised people.

Indexed as

AgedAged, 80 and overAge FactorsAgingAustraliaCross-Sectional StudiesDietary SupplementsFemaleHomes for the AgedHumansMaleNursing HomesPrevalenceResidential FacilitiesVitamin B 12Vitamin B 12 DeficiencyVitamin B 12

Identifiers

PMID22456786
PMCPMC12878079
OpenAlexW2016658942

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.