ArticleThe journal of nutrition, health & aging2012
Iron deficiency can cause cognitive impairment in geriatric patients.
Article in The journal of nutrition, health & aging, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 1 of them a synthesis that pooled it.
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Who cites it
29 citing papers in PubMed, 1 synthesis or guideline pooled it, 73 citations in OpenAlex.
- Chemical Components in the Breast Milk of Passive Smoker Women: A Systematic Review and Health Risks Assessment.Biological trace element research · 2025Pooled it
- The Association Between Hemoglobin Level and Cognitive Function in Older Adults During Hospitalization: A Prospective Observational Study.Health science reports · 2026Article
- Iron deficiency and dementia risk: evidence from the Swedish population-based cohort study AMORIS.BMC medicine · 2026Article
- A DGA-aligned pulse-protein diet may support iron homeostasis in older adults: an exploratory analysis of the PRODMED1 trial.Frontiers in nutrition · 2026Article
- Nutritional psychiatry for hypertensive older adults.World journal of psychiatry · 2025Article
- Cognitive Function in Peri- and Postmenopausal Women: Implications for Considering Iron Supplementation.Nutrients · 2025Review
- Article
- Plant-based dietary patterns and the risk of dementia: a population-based study.Age and ageing · 2023Article
- Restless leg syndrome and risk of all-cause dementia: a nationwide retrospective cohort study.Alzheimer's research & therapy · 2023Article
- The Association between Dietary Iron Intake and Incidence of Dementia in Adults Aged 60 Years or over in the UK Biobank.Nutrients · 2023Article
- Prevalence and incidence of iron deficiency in European community-dwelling older adults: an observational analysis of the DO-HEALTH trial.Aging clinical and experimental research · 2022Observational
- Iron deficiency is related to low functional outcome in patients at early rehabilitation after acute stroke.Journal of cachexia, sarcopenia and muscle · 2022Observational
- A nomogram incorporating red blood cell indices to predict post-stroke cognitive impairment in the intracerebral hemorrhage population.Frontiers in aging neuroscience · 2022Article
- Cognitive Status and Nutritional Markers in a Sample of Institutionalized Elderly People.Frontiers in aging neuroscience · 2022Article
- Cognitive Impairment in Acute Heart Failure: Narrative Review.Journal of cardiovascular development and disease · 2021Review
- Red Cell Distribution Width and Dementia Among Rural-Dwelling Older Adults: The MIND-China Study.Journal of Alzheimer's disease : JAD · 2021Article
- Iron Status is Associated with Mood, Cognition, and Functional Ability in Older Adults: A Cross-Sectional Study.Nutrients · 2020Article
- Anemia and incidence of dementia in patients with new-onset type 2 diabetes: a nationwide population-based cohort study.BMJ open diabetes research & care · 2020Article
- Red Cell Distribution Width Is Directly Associated with Poor Cognitive Performance among Nonanemic, Middle-Aged, Urban Adults.The Journal of nutrition · 2020Article
- Editorial: Anemia of Old Age.The journal of nutrition, health & aging · 2019Article
Corrections and comments
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesDeficiency of iron, which plays an important role in oxygen transport and storage, may lead to cerebral hypoxia and cognitive decline. This relationship which was studied in children and adults was not evaluated in the elderly. The objective of this study is to examine the effect of iron deficiency on cognitive function in the elderly. DESIGN, SETTING,
participantsThis is a cross-sectional study conducted in a geriatric medicine outpatient clinic of a university hospital. Consecutive 2009 patients admitted to Geriatric Medicine outpatient clinic were examined and 622 patients who fulfilled the inclusion criteria were enrolled in the study. MEASUREMENTS: Comprehensive geriatric assessment, cognitive assessment and laboratory analysis including blood count, iron, total iron binding capacity, ferritin, and transferrin saturation were performed.
resultsMean age of the study group was 72.5±6.5 and 439 (70.6%) were women. MMSE scores were moderately and significantly correlated with iron levels (r=0.33, p<0.001) and transferrin saturation (r=0.32, p<0.001). Transferrin saturation was significantly lower in the patients with dementia (p=0.040). It was found that patients with iron deficiency had lower MMSE scores (p<0.001) and this relationship was also present in patients without anemia (p=0.004).
conclusionThe results of this study revealed a negative influence of iron deficiency on cognitive function and this influence was independent from the presence of anemia. As iron deficiency can be easily diagnosed and treated, detecting its effect on cognitive function is of importance. Screening for iron deficiency and initiating appropriate treatment should be a routine part of comprehensive geriatric assessment.
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