The role of ATM in response to metformin treatment and activation of AMPK.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

11 citing papers in PubMed.

1. Metformin as an Adjunctive Therapy for Pancreatic Cancer: A Review of the Literature on Its Potential Therapeutic Use.Digestive diseases and sciences · 2018
   Review
2. Pharmacogenetics of Antidiabetic Drugs.Advances in pharmacology (San Diego, Calif.) · 2018
   Review
3. A spatiotemporal hypothesis for the regulation, role, and targeting of AMPK in prostate cancer.Nature reviews. Urology · 2017
   Review
4. A role for ataxia telangiectasia mutated in insulin-independent stimulation of glucose transport.Trends in cell & molecular biology · 2017
   Article
5. Metformin pharmacogenomics: biomarkers to mechanisms.Diabetes · 2014 · on this map
   Article
6. Metformin pharmacogenomics: current status and future directions.Diabetes · 2014 · on this map
   Article
7. AMP-activated protein kinase (AMPK) beyond metabolism: a novel genomic stress sensor participating in the DNA damage response pathway.Cancer biology & therapy · 2014
   Review
8. The role of pharmacogenetics in drug disposition and response of oral glucose-lowering drugs.Clinical pharmacokinetics · 2013
   Review
9. Metabolomic fingerprint reveals that metformin impairs one-carbon metabolism in a manner similar to the antifolate class of chemotherapy drugs.Aging · 2012
   Article
10. The role of ATM in response to metformin treatment and activation of AMPK.Nature genetics · 2012
    Article
11. Alterations in cellular energy metabolism associated with the antiproliferative effects of the ATM inhibitor KU-55933 and with metformin.PloS one · 2012
    Article

Corrections and comments

• Commented on by
  The role of ATM in response to metformin treatment and activation of AMPK.2012
• Comment on
  Common variants near ATM are associated with glycemic response to metformin in type 2 diabetes.2011

Authors and funding

3 authors.

Funding

Abstract

PubMed holds no abstract for this paper.

Indexed as