ArticleInternational journal of circumpolar health2012
Vitamin D deficiency among northern Native Peoples: a real or apparent problem?
Article in International journal of circumpolar health, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
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Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it, 35 citations in OpenAlex.
- Bone mineral content among Inuit - a systematic review of data.International journal of circumpolar health · 2025Pooled it
- Review
- Effect of Vitamin D Supplementation on Oxidative Stress Biomarkers in Women Following Religious or Intermittent Fasting Patterns.Nutrients · 2025Article
- Physiologically Based Pharmacokinetic Modelling of Serum 25-Hydroxyvitamin D Concentrations in Schoolchildren Receiving Weekly Oral Vitamin DNutrients · 2025Article
- The Problem of Vitamin D Scarcity: Cultural and Genetic Solutions by Indigenous Arctic and Tropical Peoples.Nutrients · 2022Review
- Review
- Vitamin D Status of the British African-Caribbean Residents: Analysis of the UK Biobank Cohort.Nutrients · 2021Article
- Notable Developments for Vitamin D Amid the COVID-19 Pandemic, but Caution Warranted Overall: A Narrative Review.Nutrients · 2021Review
- Article
- Vitamin D Knowledge, Attitudes, and Behaviors in Young Danish Women with a Non-Western Ethnic Minority Background-A Questionnaire Survey.International journal of environmental research and public health · 2020Article
- Linkage and association analysis of circulating vitamin D and parathyroid hormone identifies novel loci in Alaska Native Yup'ik people.Genes & nutrition · 2016Article
- Food insecurity, vitamin D insufficiency and respiratory infections among Inuit children.International journal of circumpolar health · 2016Article
- Vitamin D, serum 25(OH)D, LL-37 and polymorphisms in a Canadian First Nation population with endemic tuberculosis.International journal of circumpolar health · 2015Article
- Adequate vitamin D levels in a Swedish population living above latitude 63°N: The 2009 Northern Sweden MONICA study.International journal of circumpolar health · 2015Article
- Vitamin D status of northern indigenous people of Russia leading traditional and "modernized" way of life.International journal of circumpolar health · 2014Article
- Vitamin D status in Greenland--dermal and dietary donations.International journal of circumpolar health · 2013Review
- Re: Vitamin D deficiency among northern Native Peoples.International journal of circumpolar health · 2012Article
- Reply to W.B. Grant 'Re: Vitamin D deficiency among northern Native Peoples'.International journal of circumpolar health · 2012Article
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1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Vitamin D deficiency seems to be common among northern Native peoples, notably Inuit and Amerindians. It has usually been attributed to: (1) higher latitudes that prevent vitamin D synthesis most of the year; (2) darker skin that blocks solar UVB; and (3) fewer dietary sources of vitamin D. Although vitamin D levels are clearly lower among northern Natives, it is less clear that these lower levels indicate a deficiency. The above factors predate European contact, yet pre-Columbian skeletons show few signs of rickets-the most visible sign of vitamin D deficiency. Furthermore, because northern Natives have long inhabited high latitudes, natural selection should have progressively reduced their vitamin D requirements. There is in fact evidence that the Inuit have compensated for decreased production of vitamin D through increased conversion to its most active form and through receptors that bind more effectively. Thus, when diagnosing vitamin D deficiency in these populations, we should not use norms that were originally developed for European-descended populations who produce this vitamin more easily and have adapted accordingly.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.