Evidence map›Paper›PMID 22455544›Full record

Trial reportJournal of alternative and complementary medicine (New York, N.Y.)2012

A model of integrative care for low-back pain.

David M Eisenberg, Julie E Buring, Andrea L Hrbek, Roger B Davis, Maureen T Connelly, Daniel C Cherkin, Donald B Levy, Mark Cunningham, Bonnie O'Connor, Diana E Post

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of alternative and complementary medicine (New York, N.Y.), 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 3 pooled it
16.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 3 syntheses or guidelines pooled it, 45 citations in OpenAlex.

  1. Models of care for managing non-specific low back pain.The Cochrane database of systematic reviews · 2025
    Pooled it
  2. Pooled it
  3. Herbal medicine for low-back pain.The Cochrane database of systematic reviews · 2014
    Pooled it
  4. Trial
  5. Article
  6. Article
  7. Review
  8. Associations of Early Treatments for Low-Back Pain with Military Readiness Outcomes.Journal of alternative and complementary medicine (New York, N.Y.) · 2018
    Article
  9. Establishing an Integrative Medicine Program Within an Academic Health Center: Essential Considerations.Academic medicine : journal of the Association of American Medical Colleges · 2016
    Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Salutogenesis: the defining concept for a new healthcare system.Global advances in health and medicine · 2014
    Article
  15. Article
  16. Article
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 1 country.

David M EisenbergDivision of General Medicine and Primary Care, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02115, USA. David_Eisenberg@hms.harvard.edu
Julie E Buring
Andrea L Hrbek
Roger B Davis
Maureen T Connelly
Daniel C Cherkin
Donald B Levy
Mark Cunningham
Bonnie O'Connor
Diana E Post
Harvard University · USBrigham and Women's Hospital · USBeth Israel Deaconess Medical Center · USBrown University · USKaiser Permanente Washington Health Research Institute · US

Funding

Use and Effectiveness of a Model Integrative Care Clinic in an Academic HospitalR01AT005065 · NCCIH · BRIGHAM AND WOMEN'S HOSPITAL · PI BURING, JULIE E., WAYNE, PETER MICHAEL · 2010 to 2014
$3.1M
Model of Integrative Care In An Academic Health CenterR01AT000905 · NCCIH · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI EISENBERG, DAVID M · 2001 to 2004
$1.9M
NCCIH NIH HHS AT005065NCCIH NIH HHS AT00905NCCIH NIH HHS R01 AT005065
6 · The paper itself

Abstract

objectivesWhile previous studies focused on the effectiveness of individual complementary and alternative medical (CAM) therapies, the value of providing patients access to an integrated program involving multiple CAM and conventional therapies remains unknown. The objective of this study is to explore the feasibility and effects of a model of multidisciplinary integrative care for subacute low-back pain (LBP) in an academic teaching hospital.

designThis was a pilot randomized trial comparing an individualized program of integrative care (IC) plus usual care to usual care (UC) alone for adults with LBP. SUBJECTS: Twenty (20) individuals with LPB of 3-12 weeks' duration were recruited from an occupational health clinic and community health center.

interventionsParticipants were randomized to 12 weeks of individualized IC plus usual care versus UC alone. IC was provided by a trained multidisciplinary team offering CAM therapies and conventional medical care. OUTCOME MEASURES: The outcome measures were symptoms (pain, bothersomeness), functional status (Roland-Morris score), SF-12, worry, and difficulty performing three self-selected activities.

resultsOver 12 weeks, participants in the IC group had a median of 12.0 visits (range 5-25). IC participants experienced significantly greater improvements at 12 weeks than those receiving UC alone in symptom bothersomeness (p=0.02) and pain (p=0.005), and showed greater improvement in functional status (p=0.08). Rates of improvement were greater for patients in IC than UC in functional status (p=0.02), bothersomeness (p=0.002), and pain scores (p=0.001). Secondary outcomes of self-selected most challenging activity, worry, and the SF-12 also showed improvement in the IC group at 12 weeks. These differences persisted at 26 weeks, but were no longer statistically significant.

conclusionsIt was feasible for a multidisciplinary, outpatient IC team to deliver coordinated, individualized intervention to patients with subacute LBP. Results showed a promising trend for benefit of treating patients with persistent LBP with this IC model, and warrant evaluation in a full-scale study.

Indexed as

Activities of Daily LivingComplementary TherapiesIntegrative MedicinePain ManagementPatient Care TeamAdultFemaleHumansLow Back PainMaleMiddle AgedOutcome Assessment, Health CarePilot Projects

Identifiers

PMID22455544
PMCPMC3326266
OpenAlexW2087362513

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.