ArticleJournal of ophthalmic & vision research2011
Functional assessment of magno, parvo and konio-cellular pathways; current state and future clinical applications.
Article in Journal of ophthalmic & vision research, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed.
- No Unique Magnocellular Facilitation in Parafoveal Processing: A Combined EEG and Eye Tracking Study.Neurobiology of language (Cambridge, Mass.) · 2026Article
- Visual Function in Alzheimer's Disease: Current Understanding and Potential Mechanisms Behind Visual Impairment.Journal of clinical medicine · 2025Review
- Visual Neuroplasticity: Modulating Cortical Excitability with Flickering Light Stimulation.Journal of imaging · 2025Article
- Pupil responses to colorfulness are selectively reduced in healthy older adults.Scientific reports · 2023Article
- Evidence for adaptive myelination of subcortical shortcuts for visual motion perception in healthy adults.Human brain mapping · 2023Article
- Cell death in the lateral geniculate nucleus, and its possible relationship with nicotinic receptors and sudden infant death syndrome (SIDS).Molecular neurobiology · 2023Article
- Disruption of early visual processing in amyloid-positive healthy individuals and mild cognitive impairment.Alzheimer's research & therapy · 2023Article
- A Reflection Upon the Contribution of Retinal and Cortical Electrophysiology to Time of Information Processing in Psychiatric Disorders.Frontiers in psychiatry · 2022Article
- Age- and frequency-dependent changes in dynamic contrast perception in visual snow syndrome.The journal of headache and pain · 2021Article
- Studying Cortical Plasticity in Ophthalmic and Neurological Disorders: From Stimulus-Driven to Cortical Circuitry Modeling Approaches.Neural plasticity · 2019Review
- Tobacco Use Decreases Visual Sensitivity in Schizophrenia.Frontiers in psychology · 2018Article
- Colour discrimination thresholds in type 1 Bipolar Disorder: a pilot study.Scientific reports · 2017Article
- Functional mapping of the magnocellular and parvocellular subdivisions of human LGN.NeuroImage · 2014Article
- Spectral and spatial selectivity of luminance vision in reef fish.Frontiers in neural circuits · 2014Article
- Alzheimer's disease: screening biomarkers using frequency doubling technology visual field.ISRN neurology · 2013Article
- Psychophysical Evidence for Impaired Magno, Parvo, and Konio-cellular Pathways in Dyslexic Children.Journal of ophthalmic & vision researchArticle
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The information generated by cone photoreceptors in the retina is compressed and transferred to higher processing centers through three distinct types of ganglion cells known as magno, parvo and konio cells. These ganglion cells, which travel from the retina to the lateral geniculate nucleus (LGN) and then to the primary visual cortex, have different structural and functional characteristics, and are organized in distinct layers in the LGN and the primary visual cortex. Magno cells are large, have thick axons and usually collect input from many retinal cells. Parvo cells are smaller, with fine axons and less myelin than mango cells. Konio cells are diverse small cells with wide fields of input consisting of different cells types. The three cellular pathways also differ in function. Magno cells respond rapidly to changing stimuli, while parvo cells need time to respond. The distinct patterns of structure and function in these cells have provided an opportunity for clinical assessment of their function. Functional assessment of these cells is currently used in the field of ophthalmology where frequency-doubling technology perimetry selectively assesses the function of magno cells. Evidence has accrued that the three pathways show characteristic patterns of malfunctions in multiple sclerosis, schizophrenia, Parkinson's and Alzheimer's diseases, and several other disorders. The combination of behavioral assessment with other techniques, such as event related potentials and functional magnetic resonance imaging, seems to bear promising future clinical applications.
Indexed as
Identifiers
22454721PMC3306093What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.