ArticleClinical research in cardiology : official journal of the German Cardiac Society2012
Prognostic relevance of heart rate at rest for survival and the quality of life in patients with dilated cardiomyopathy.
Article in Clinical research in cardiology : official journal of the German Cardiac Society, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 20 citations in OpenAlex.
- Betaferon in chronic viral cardiomyopathy (BICC) trial: Effects of interferon-β treatment in patients with chronic viral cardiomyopathy.Clinical research in cardiology : official journal of the German Cardiac Society · 2016Trial
- Anesthetic Management of Patients with Dilated Cardiomyopathy Undergoing Noncardiac Surgery.Medicina (Kaunas, Lithuania) · 2023Review
- Novel drugs for heart rate control in heart failure.Heart failure reviews · 2018Review
- Endomyocardial expression of SDF-1 predicts mortality in patients with suspected myocarditis.Clinical research in cardiology : official journal of the German Cardiac Society · 2015Article
- Cheyne-Stokes respiration in heart failure: friend or foe? Hemodynamic effects of hyperventilation in heart failure patients and healthy volunteers.Clinical research in cardiology : official journal of the German Cardiac Society · 2015Article
- Effects of β-blocker therapy on electrocardiographic and echocardiographic characteristics of left ventricular noncompaction.Clinical research in cardiology : official journal of the German Cardiac Society · 2015Article
- Novel and nonpharmacologic approaches to cardio-protection in hypertension.Current hypertension reports · 2014Review
- Cardiac magnetic resonance imaging in patients undergoing percutaneous mitral valve repair with the MitraClip system.Clinical research in cardiology : official journal of the German Cardiac Society · 2014Article
- Portable recording for detecting sleep disorder breathing in patients under the care of a heart failure clinic.Clinical research in cardiology : official journal of the German Cardiac Society · 2013Article
- Electrical myostimulation improves left ventricular function and peak oxygen consumption in patients with chronic heart failure: results from the exEMS study comparing different stimulation strategies.Clinical research in cardiology : official journal of the German Cardiac Society · 2013Article
- Effects of carvedilol therapy on cardiac autonomic control, QT dispersion, and ventricular arrhythmias in children with dilated cardiomyopathy.Medical science monitor : international medical journal of experimental and clinical research · 2013Article
- Ivabradine: potential clinical applications in critically ill patients.Clinical research in cardiology : official journal of the German Cardiac Society · 2013Review
Corrections and comments
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Authors and funding
8 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesReduction of resting heart rate (HR) has been suggested as a novel therapeutic approach in patients with chronic heart failure because it has been shown to prolong survival and also to improve health-related quality of life (Hr-QoL). The purpose of this analysis was to assess the prognostic impact of resting HR in patients with dilated cardiomyopathy (DCM).
methods217 patients with DCM confirmed by endomyocardial biopsy were investigated (age 49 ± 11 years, 20.7 % were female). The study population was divided into two groups according to the median of the resting HR. After a median follow-up time of 7.4 years overall survival and health-related quality of life (Hr-QoL) were compared in both groups. Survival was compared using Kaplan-Meier method and Hr-QoL was assessed using the Minnesota Living with Heart Failure Questionnaire (MLHFQ).
resultsElevated resting HR was associated with poor 1-year survival (p = 0.03). In contrast, long-term survival was not affected by HR (p = 0.20). Patients with lower HR at rest scored significantly lower on the MLHFQ (20 vs. 36, p = 0.03), indicating that higher resting HR is associated with an impairment of Hr-QoL.
conclusionsIncreased HR might be used as a diagnostic tool to identify patients at risk. Reduction of resting HR in patients with DCM might be a therapeutic option to improve Hr-QoL and therefore merits further investigation in future studies.
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