ReviewAdvances in experimental medicine and biology2012
Elementary calcium release events from the sarcoplasmic reticulum in the heart.
Review in Advances in experimental medicine and biology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
8 citing papers in PubMed.
- Electrophysical cardiac remodeling at the molecular level: Insights into ryanodine receptor activation and calcium-induced calcium release from a stochastic explicit-particle model.Biophysical journal · 2024Article
- Modeling sarcoplasmic reticulum CaBiophysics reports · 2024Article
- Assaying sarcoplasmic reticulum CaBiophysics reports · 2024Article
- Hypertrophic cardiomyopathy is characterized by alterations of the mitochondrial calcium uniporter complex proteins: insights from patients with aortic valve stenosis versus hypertrophic obstructive cardiomyopathy.Frontiers in pharmacology · 2023Article
- The calcium-cancer signalling nexus.Nature reviews. Cancer · 2017Review
- Calcitox-aging counterbalanced by endogenous farnesol-like sesquiterpenoids: An undervalued evolutionarily ancient key signaling pathway.Communicative & integrative biology · 2017Article
- NOX2 As a Target for Drug Development: Indications, Possible Complications, and Progress.Antioxidants & redox signaling · 2015Review
- Assessment of calcium sparks in intact skeletal muscle fibers.Journal of visualized experiments : JoVE · 2014Article
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
Ca(2+) release events underlie global Ca(2+) signaling yet they are regulated by local, subcellular signaling features. Here we review the latest developments of different elementary Ca(2+) release features that include Ca(2+) sparks, Ca(2+) blinks (the corresponding depletion of Ca(2+) in the sarcoplasmic reticulum (SR) during a spark) and the recently identified small Ca(2+) release events called quarky SR Ca(2+) release (QCR). QCR events arise from the opening of only a few type 2 ryanodine receptors (RyR2s) - possibly only one. Recent reports suggest that QCR events can be commingled with Ca(2+) sparks and may thus explain some variations observed in Ca(2+) sparks. The Ca(2+) spark termination mechanism and the number of RyR2 channels activated during a Ca(2+) spark will be discussed with respect to both Ca(2+) sparks and QCR events.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.