ArticleMolecules (Basel, Switzerland)2012
Protective effect of ischemic postconditioning against ischemia reperfusion-induced myocardium oxidative injury in IR rats.
Article in Molecules (Basel, Switzerland), 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 29 citations in OpenAlex.
- Simvastatin Improves Myocardial Ischemia Reperfusion Injury through KLF-Regulated Alleviation of Inflammation.Disease markers · 2022Article
- Ischaemic post-conditioning in rats: Responder and non-responder differ in transcriptome of mitochondrial proteins.Journal of cellular and molecular medicine · 2020Article
- Ischemic postconditioning reduced myocardial ischemia-reperfusion injury: The roles of melatonin and uncoupling protein 3.Anatolian journal of cardiology · 2020Article
- Transcriptional Alterations by Ischaemic Postconditioning in a Pig Infarction Model: Impact on Microvascular Protection.International journal of molecular sciences · 2019Article
- Sufentanil protects the rat myocardium against ischemia-reperfusion injury via activation of the ERK1/2 pathway.Cytotechnology · 2018Article
- Application of ischemic postconditioning's algorithms in tissues protection: response to methodological gaps in preclinical and clinical studies.Journal of cellular and molecular medicine · 2017Article
- Effects of Sanguis Draconis on Perforator Flap Survival in Rats.Molecules (Basel, Switzerland) · 2016Article
- Molecular Characterization of Reactive Oxygen Species in Myocardial Ischemia-Reperfusion Injury.BioMed research international · 2015Review
- Rapamycin reverses paraquat-induced acute lung injury in a rat model through inhibition of NFκB activation.International journal of clinical and experimental pathology · 2015Article
- Anaesthetic Postconditioning at the Initiation of CPR Improves Myocardial and Mitochondrial Function in a Pig Model of Prolonged Untreated Ventricular Fibrillation.Resuscitation · 2014Article
- Evolving possible link between PI3K and NO pathways in neuroprotective mechanism of ischemic postconditioning in mice.Molecular and cellular biochemistry · 2014Article
- Intermedin protects against myocardial ischemia-reperfusion injury in diabetic rats.Cardiovascular diabetology · 2013Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Brief episodes of myocardial ischemia-reperfusion (IR) employed during reperfusion after a prolonged ischemic insult may attenuate the total ischemia-reperfusion injury. This phenomenon has been termed ischemic postconditioning. In the present study, we studied the possible effect of ischemic postconditioning on an ischemic reperfusion (IR)-induced myocardium oxidative injury in rat model. Results showed that ischemic postconditioning could improve arrhythmia cordis, reduce myocardium infarction and serum creatin kinase (CK), lactate dehydrogenase (LDH) and aspartate transaminase (AST) activities in IR rats. In addition, ischemic postconditioning could still decrease myocardium malondialdehyde (MDA) level, and increased myocardium Na+-K+-ATPase, Ca2+-Mg2+-ATPase, superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GSH-Px) and glutathione reductase (GR) activities. It can be concluded that ischemic postconditioning possesses strong protective effects against ischemia reperfusion-induced myocardium oxidative injury in IR rats.
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