Trial reportGeneral thoracic and cardiovascular surgery2012
Inhalation of corticosteroid and β-agonist for persistent cough following pulmonary resection.
Trial report in General thoracic and cardiovascular surgery, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
15 citing papers in PubMed, 19 citations in OpenAlex.
- Effects of Combined Use of Salbutamol/Budesonide in Thoracic Surgery on Postoperative Myocardial Injury (MINS) - A Prospective Randomized Clinical Trial.Drug design, development and therapy · 2023Trial
- Exploratory research on drugs after lung surgery based on real-world data from the FDA adverse event reporting system database.PloS one · 2026Article
- Quality of life in older adults (aged 60-80 years) after lung cancer surgery: a longitudinal observational study.Health and quality of life outcomes · 2025Observational
- Article
- Budesonide/glycopyrronium/formoterol fumarate co-suspension metered dose inhaler relieves cough after lobectomy: a randomized controlled study.Translational lung cancer research · 2025Article
- Multidisciplinary international expert consensus on perioperative airway management.Translational lung cancer research · 2025Review
- Exploring the symptoms and psychological experiences among lung cancer convalescence patients after radical lobectomy: A qualitative study.Cancer medicine · 2024Article
- Review
- Risk factors for cough after pulmonary resection.World journal of surgical oncology · 2023Article
- Discrepancy in the perception of symptoms among patients and healthcare providers after lung cancer surgery.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2022Article
- Bronchial morphological changes are associated with postoperative intractable cough after right upper lobectomy in lung cancer patients.Quantitative imaging in medicine and surgery · 2022Article
- Risk factors of cough in non-small cell lung cancer patients after video-assisted thoracoscopic surgery.Journal of thoracic disease · 2018Article
- Modelling the asthma phenotype: impact of cigarette smoke exposure.Respiratory research · 2018Article
- Lung protective effects of budesonide nebulization during perioperative period of thoracolumbar fusion.Journal of thoracic disease · 2014Article
- Pulmonary Rehabilitation Exercises Effectively Improve Chronic Cough After Surgery for Non-small Cell Lung Cancer.Cancer control : journal of the Moffitt Cancer CenterArticle
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPatients undergoing pulmonary resection often suffer from a dry, hacking cough, which is usually refractory to opioid cough suppressors such as codeine. The cough is often painful and impairs the quality of life of the patients. The efficacy of an inhaled corticosteroid plus β2-agonist against the persistent cough after pulmonary resection was evaluated in this study.
methodsWe enrolled 21 patients in this prospective study of the efficacy of an inhaled corticosteroid plus β2-agonist against persistent cough following pulmonary resection. After baseline evaluation of the severity of the postoperative persistent cough using a visual analog scale (VAS), treatment with an inhaled corticosteroid plus β2-agonist was initiated and continued for 2 weeks. At the end of the 2 weeks, the cough severity was evaluated again using a VAS.
resultsThe median grade of cough on the VAS before the start of the inhaled treatment was 4 (range 3-8). At the end of 2 weeks of treatment with an inhaled corticosteroid plus β2 agonist, the median grade of cough on the VAS decreased from 4 to 1 (range 0-4). As an adverse effect of the inhalation, hoarseness was observed in one patient, which disappeared promptly after discontinuing the inhalations.
conclusionTreatment with an inhaled corticosteroid plus β2 agonist appeared to be highly effective, without severe adverse effects, against the persistent cough suffered by patients after pulmonary resection.
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