Evidence map›Paper›PMID 22453500›Full record

ArticleParasitology research2012

Purification and cellular localization of the Entamoeba histolytica transcarboxylase.

E Barbosa-Cabrera, A Salas-Casas, S Rojas-Hernández, A Jarillo-Luna, E Abarca-Rojano, M A Rodríguez, R Campos-Rodríguez

Abstract read
PubMed Publisher
In one paragraph

Article in Parasitology research, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact, top 88% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. The American journal of tropical medicine and hygiene · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

E Barbosa-CabreraSección de Estudios de Posgrado e Investigación, Escuela Superior de Medicina, Instituto Politécnico Nacional, Plan de San Luís y Díaz Mirón, CP 11340, Mexico, D.F., Mexico.
A Salas-Casas
S Rojas-Hernández
A Jarillo-Luna
E Abarca-Rojano
M A Rodríguez
R Campos-Rodríguez
Instituto Politécnico Nacional · MX

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Genome analysis of Entamoeba histolytica predicts the presence of acetyl-CoA carboxylase. Using Western blot, histochemistry, and confocal microscopy, we demonstrated the presence of a biotin-containing protein in the cytoplasm of E. histolytica, with a molecular weight of 136 kDa and biotin-carboxylase activity. This protein probably corresponds to a transcarboxylase that catalyzes the rate-limiting reaction leading to fatty acid elongation.

Indexed as

AnimalsCarboxyl and Carbamoyl TransferasesEntamoeba histolyticaGene Expression Regulation, EnzymologicGenome, ProtozoanProtozoan ProteinsCarboxyl and Carbamoyl TransferasesMethylmalonyl-CoA carboxytransferaseProtozoan Proteins

Identifiers

PMID22453500
OpenAlexW2111146634

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.