ArticleBMC public health2012
Anxiety and depression amongst patients enrolled in a public sector antiretroviral treatment programme in South Africa: a cross-sectional study.
Article in BMC public health, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 59 papers, 7 of them syntheses that pooled it.
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Who cites it
59 citing papers in PubMed, 7 syntheses or guidelines pooled it, 118 citations in OpenAlex.
- Primary-level and community worker interventions for the prevention of mental disorders and the promotion of well-being in low- and middle-income countries.The Cochrane database of systematic reviews · 2023Pooled it
- What constitutes a palliative care need in people with serious illnesses across Africa? A mixed-methods systematic review of the concept and evidence.Palliative medicine · 2021Pooled it
- Burden of Depression in Outpatient HIV-Infected adults in Sub-Saharan Africa; Systematic Review and Meta-analysis.AIDS and behavior · 2020Pooled it
- Interventions and approaches to integrating HIV and mental health services: a systematic review.Health policy and planning · 2017Pooled it
- Pooled it
- Impact of support groups for people living with HIV on clinical outcomes: a systematic review of the literature.Journal of acquired immune deficiency syndromes (1999) · 2015Pooled it
- Reliability and validity of depression assessment among persons with HIV in sub-Saharan Africa: systematic review and meta-analysis.Journal of acquired immune deficiency syndromes (1999) · 2014Pooled it
- Prevalence of depression and associated factors among HIV/AIDS Patients on HAART in Okugu Refugee Camp, Gambella, Ethiopia.Frontiers in psychiatry · 2025Article
- HIV-related stigma and psychological distress in a cohort of patients receiving antiretroviral therapy in Nigeria.AIDS care · 2024Article
- Adverse childhood experiences, traumatic events, and mental health among adults at two outpatient psychiatric facilities in Johannesburg, South Africa: a cross-sectional analysis.BMC psychiatry · 2023Article
- Conjoint tobacco and alcohol use and depression among HIV-positive patients in Sedibeng, South Africa.South African family practice : official journal of the South African Academy of Family Practice/Primary Care · 2023Article
- Prevalence of and factors associated with depression among adult patients living with HIV/AIDs undergoing ART unit in Banadir hospital, Mogadishu Somalia.BMC psychiatry · 2023Article
- The Relation between Depressive Symptoms and Unsafe Sex among MSM Living with HIV.International journal of environmental research and public health · 2023Article
- Article
- Sleep quality, social rhythms, and depression among people living with HIV: a path analysis based on social zeitgeber theory.Frontiers in psychiatry · 2023Article
- Risky sexual behaviors and associated factors among adult patients on antiretroviral treatment at Mankweng Hospital in Limpopo Province, South Africa.Frontiers in public health · 2023Article
- Intimate partner violence and HIV treatment adherence in urban South Africa: Mediating role of perinatal common mental disorders.SSM. Mental health · 2022Article
- Functioning Problems Associated with Health Conditions with Greatest Disease Burden in South Africa: A Scoping Review.International journal of environmental research and public health · 2022Article
- Development and Initial Feasibility of a Hospital-Based Acceptance and Commitment Therapy Intervention to Improve Retention in Care for Out-of-Care Persons with HIV: Lessons Learned from an Open Pilot Trial.Journal of clinical medicine · 2022Article
- Depression symptoms, HIV testing, linkage to ART, and viral suppression among women in a high HIV burden district in KwaZulu-Natal, South Africa: A cross-sectional household study.Journal of health psychology · 2022Article
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundHIV/AIDS and depression are projected to be the two leading causes of disability by 2030. HIV/AIDS and anxiety/depression are interlinked. People suffering from depression may be more likely to engage in risky sexual behaviour, and therefore at greater risk of contracting HIV. An HIV + diagnosis may trigger symptoms of anxiety and depression, which may in turn result in risky sexual behaviour and the spread of HIV. This study explores correlates of anxiety and depression in patients enrolled in a public sector ART programme in South Africa.
methodsInterviews were conducted with 716 patients initiating ART at twelve public health care facilities in the Free State. Symptoms of anxiety and depression were measured using the Hospital Anxiety and Depression Scale (HADS). An 8+ cut-off was used to identify possible cases of anxiety and depression. Multivariate logistic regression analysis, using STATA Version 11, was performed to identify correlates of anxiety and depression.
resultsThe prevalence of symptoms of respectively anxiety and depression amongst this study population in the Free State was 30.6% and 25.4%. The multivariate logistic regression analyses identified five correlates of symptoms of anxiety and depression. Disruptive side effects (OR = 3.62, CI 1.95-6.74) and avoidant coping (OR = 1.42, CI 1.22-1.65) were associated with a greater number of symptoms of anxiety. Stigma was associated with an increase in symptoms of anxiety (OR = 1.14, CI 1.07-1.21) and of depression (OR = 1.13, CI 1.06-1.20), while being a widow (OR = 0.30, CI 0.13-0.69) and participating in a support group (OR = 0.21, CI 0.05-0.99) were associated with decreased symptoms of depression.
conclusionsThe findings from the study provide valuable insights into the psychosocial aspects of the Free State public-sector ART programme. Combined with the literature on the intricate link between mental health problems and treatment outcomes our results emphasise firstly, the necessity that resources be allocated for both screening and treating mental health problems and, secondly, the need for interventions that will encourage support-group participation, address ART side effects, reduce maladaptive coping styles, and minimise the stigma associated with symptoms of anxiety and/or depression.
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