Evidence map›Paper›PMID 22452663›Full record

SynthesisSports medicine (Auckland, N.Z.)2012

Cardiopulmonary exercise testing in cancer rehabilitation: a systematic review.

Charlotte N Steins Bisschop, Miranda J Velthuis, Harriët Wittink, Kees Kuiper, Tim Takken, Wout J T M van der Meulen, Eline Lindeman, Petra H M Peeters, Anne M May

Abstract readSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Sports medicine (Auckland, N.Z.), 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Trial
  4. Smartphone measurements of physical activity and fitness are associated with early trial discontinuation of patients in (hemato)oncology phase I/II clinical trials.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2021
    Trial
  5. Trial
  6. Trial
  7. Trial
  8. Trial
  9. Trial
  10. Review
  11. Article
  12. Association between PhA and Physical Performance Variables in Cancer Patients.International journal of environmental research and public health · 2023
    Article
  13. Review
  14. Article
  15. Article
  16. BMC sports science, medicine & rehabilitation · 2020
    Article
  17. Article
  18. Cardiorespiratory fitness and muscle strength in pancreatic cancer patients.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2017
    Article
  19. Exercise for people with cancer: a systematic review.Current oncology (Toronto, Ont.) · 2017
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Charlotte N Steins BisschopJulius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, the Netherlands. c.n.steinsbisschop@umcutrecht.com
Miranda J Velthuis
Harriët Wittink
Kees Kuiper
Tim Takken
Wout J T M van der Meulen
Eline Lindeman
Petra H M Peeters
Anne M May

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This systematic review aims to get insight into the feasibility of cardiopulmonary exercise testing (CPET) in patients with cancer prior to a physical exercise programme. We will focus on quality (defined as the adherence to international guidelines for methods of CPET) and safety of CPET. Furthermore, we compare the peak oxygen uptake (·VO(2peak)) values of patients with cancer with reference values for healthy persons to put these values into a clinical perspective. A computer aided search with 'cardiopulmonary exercise testing' and 'cancer' using MEDLINE, EMBASE, Pedro, CINAHL® and SPORTDiscus™ was carried out. We included studies in which CPET with continuous gas exchange analysis has been performed prior to a physical exercise programme in adults with cancer. Twenty studies describing 1158 patients were eligible. Reported adherence to international recommendations for CPET varied per item. In most studies, the methods of CPET were not reported in detail. Adverse events occurred in 1% of patients. The percentage ·VO(2peak) of reference values for healthy persons varied between 65% and 89% for tests before treatment, between 74% and 96% for tests during treatment and between 52% and 117% for tests after treatment. Our results suggest that CPET is feasible and seems to be safe for patients with cancer prior to a physical exercise programme. We recommend that standard reporting and quality guidelines should be followed for CPET methods. The decreased ·VO(2peak) values of patients with cancer indicate that physical exercise should be implemented in their standard care.

Indexed as

Exercise ToleranceExercise TestFeasibility StudiesHumansNeoplasms

Identifiers

PMID22452663

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.