Evidence map›Paper›PMID 22451742›Full record

ArticleHeterocycles2012

APPLICATIONS OF MULTICOMPONENT ASSEMBLY PROCESSES TO THE FACILE SYNTHESES OF DIVERSELY FUNCTIONALIZED NITROGEN HETEROCYCLES.

James R Donald, Brett A Granger, Simon Hardy, James J Sahn, Stephen F Martin

Abstract read
In one paragraph

Article in Heterocycles, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

James R DonaldDepartment of Chemistry and Biochemistry and Texas Institute for Drug and Diagnostics Development, The University of Texas at Austin, Austin, Texas 78712, United States.
Brett A Granger
Simon Hardy
James J Sahn
Stephen F Martin

Funding

SYNTHESIS OF NITROGEN-CONTAINING NATURAL PRODUCTSR01GM025439 · NIGMS · UNIVERSITY OF TEXAS AUSTIN · PI MARTIN, STEPHEN · 1985 to 2010
$2.4M
Generating Diverse Pilot-Scale Libraries for ScreeningP41GM086192 · NIGMS · UNIVERSITY OF TEXAS AT AUSTIN · PI MARTIN, STEPHEN · 2008 to 2010
$1.1M
NIGMS NIH HHS P41 GM086192NIGMS NIH HHS R01 GM025439
6 · The paper itself

Abstract

Several multicomponent assembly processes have been developed for the synthesis of intermediates that may be elaborated by a variety of cyclizations to generate a diverse array of highly functionalized heterocycles from readily-available starting materials. The overall approach enables the efficient preparation of libraries of small molecules derived from fused, privileged scaffolds.

Identifiers

PMID22451742
PMCPMC3311471

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.