Evidence map›Paper›PMID 22450978›Full record

ArticleAntimicrobial agents and chemotherapy2012

Native valve endocarditis caused by Corynebacterium striatum with heterogeneous high-level daptomycin resistance: collateral damage from daptomycin therapy?

Truc T Tran, Siraya Jaijakul, Cole T Lewis, Lorena Diaz, Diana Panesso, Heidi B Kaplan, Barbara E Murray, Audrey Wanger, Cesar A Arias

Open access · bronzeAbstract readCase Reports
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 1 pooled it
2.4field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 1 synthesis or guideline pooled it, 56 citations in OpenAlex.

  1. Antimicrobial treatment of Corynebacterium striatum invasive infections: a systematic review.Revista do Instituto de Medicina Tropical de Sao Paulo · 2021
    Pooled it
  2. Review
  3. Infectious diseases & clinical microbiology · 2025
    Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2024
    Article
  9. Article
  10. Infection and drug resistance · 2022
    Article
  11. Review
  12. Evaluating the Rapid Emergence of Daptomycin Resistance inJournal of clinical microbiology · 2021
    Article
  13. Antimicrobial Resistance and Molecular Epidemiology ofPathogens (Basel, Switzerland) · 2020
    Article
  14. Safety Evaluation of Individual Pillboxes to Control Cross-Contamination in the Drug Circuit in Hospitals.International journal of environmental research and public health · 2019
    Article
  15. Genomics of Corynebacterium striatum, an emerging multidrug-resistant pathogen of immunocompromised patients.Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases · 2018
    Article
  16. Article
  17. Antimicrobial agents and chemotherapy · 2018
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Truc T TranUniversity of Houston College of Pharmacy, Department of Internal Medicine, Division of Infectious Diseases, Houston, Texas, USA. Truc.T.Tran@uth.tmc.edu
Siraya Jaijakul
Cole T Lewis
Lorena Diaz
Diana Panesso
Heidi B Kaplan
Barbara E Murray
Audrey Wanger
Cesar A Arias
Universidad El Bosque · COThe University of Texas Health Science Center at Houston · USUniversity of Houston · US

Funding

Molecular Mechanisms Of Daptomycin Resistance In EnterococciR01AI093749 · NIAID · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI ARIAS, CESAR AUGUSTO · 2011 to 2015
$1.9M
NIAID NIH HHS R01 AI093749
6 · The paper itself

Abstract

We describe a patient who developed Corynebacterium striatum native valve endocarditis after receiving two 6-week courses of daptomycin for the treatment of methicillin-resistant Staphylococcus aureus bacteremia and osteomyelitis. The organism exhibited in vitro heteroresistance to daptomycin, with two subpopulations showing daptomycin susceptibility (MIC of ≤ 0.094 μg/ml) and high-level resistance to daptomycin (MIC of ≥ 256 μg/ml). The selection of daptomycin-resistant Gram-positive skin flora with the potential of causing invasive disease may be a concern during prolonged courses of daptomycin.

Indexed as

Anti-Bacterial AgentsBacteremiaCorynebacteriumDaptomycinDrug Resistance, BacterialEndocarditis, BacterialHumansMaleMethicillin-Resistant Staphylococcus aureusMiddle AgedOsteomyelitisAnti-Bacterial AgentsDaptomycin

Identifiers

PMID22450978
PMCPMC3370765
OpenAlexW2146417844

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.