Evidence map›Paper›PMID 22450858›Full record

ReviewCurrent opinion in endocrinology, diabetes, and obesity2012

Illicit use of androgens and other hormones: recent advances.

Gen Kanayama, Harrison G Pope

Abstract readReview
In one paragraph

Review in Current opinion in endocrinology, diabetes, and obesity, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
4.8field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 83 citations in OpenAlex.

  1. Article
  2. Nonconforming gender expression and adolescent anabolic-androgenic steroids misuse.Child and adolescent psychiatry and mental health · 2024
    Article
  3. Article
  4. The Roles of Androgens in Humans: Biology, Metabolic Regulation and Health.International journal of molecular sciences · 2022
    Review
  5. Men´s experiences of using anabolic androgenic steroids.International journal of qualitative studies on health and well-being · 2021
    Article
  6. Review
  7. Article
  8. Article
  9. Women's Experiences of Using Anabolic Androgenic Steroids.Frontiers in sports and active living · 2021
    Article
  10. Article
  11. Article
  12. Review
  13. Self-Perceived Weight and Anabolic Steroid Misuse Among US Adolescent Boys.The Journal of adolescent health : official publication of the Society for Adolescent Medicine · 2016
    Article
  14. Recruitment to doping and help-seeking behavior of eight female AAS users.Substance abuse treatment, prevention, and policy · 2016
    Article
  15. Article
  16. Synthetic androgens as designer supplements.Current neuropharmacology · 2015
    Review
  17. Review
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Gen KanayamaBiological Psychiatry Laboratory, McLean Hospital, Belmont, Massachusetts 02478, USA.
Harrison G Pope
Harvard University · USMcLean Hospital · US

Funding

Medical Consequences of Long-Term Anabolic-Androgenic Steroid AbuseR01DA029141 · NIDA · MCLEAN HOSPITAL · PI POPE, HARRISON G · 2011 to 2015
$2.5M
NIDA NIH HHS DA029141NIDA NIH HHS R01 DA029141
6 · The paper itself

Abstract

purpose of reviewTo summarize recent advances in studies of illicit use of androgens and other hormones. RECENT

findingsAndrogens and other appearance-enhancing and performance-enhancing substances are widely abused worldwide. Three notable clusters of findings have emerged in this field in recent years. First, studies almost unanimously find that androgen users engage in polypharmacy, often ingesting other hormones (e.g., human growth hormone, thyroid hormones, and insulin), ergo/thermogenic drugs (e.g., caffeine, ephedrine, and clenbuterol), and classical drugs of abuse (e.g., cannabis, opiates, and cocaine). Second, reports of long-term psychiatric and medical adverse effects of androgens continue to accumulate. In cardiovascular research particularly, controlled studies have begun to supersede anecdotal evidence, strengthening the case that androgens (possibly acting synergistically with other abused drugs) may cause significant morbidity and even mortality. Third, it is increasingly recognized that androgen use may lead to a dependence syndrome with both psychological and physiological origins. Androgen dependence likely affects some millions of individuals worldwide, and arguably represents the least studied major class of illicit drug dependence. SUMMARY: Given mounting evidence of the adverse effects of androgens and associated polypharmacy, this topic will likely represent an expanding area of research and an issue of growing public health concern.

Indexed as

AdolescentAdultAndrogensBehavioral SymptomsCardiovascular DiseasesDietary SupplementsFemaleFitness CentersHumansHypogonadismMalePerformance-Enhancing SubstancesPublic HealthSubstance-Related DisordersYoung AdultAndrogensPerformance-Enhancing Substances

Identifiers

PMID22450858
PMCPMC3337343
OpenAlexW2165918622

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.