Evidence map›Paper›PMID 22450149›Full record

ReviewCurrent opinion in oncology2012

Active surveillance for prostate cancer: past, present and future.

Eric A Singer, Aradhana Kaushal, Baris Turkbey, Anna Couvillon, Peter A Pinto, Howard L Parnes

Abstract readReview
In one paragraph

Review in Current opinion in oncology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Clonal evaluation of prostate cancer foci in biopsies with discontinuous tumor involvement by dual ERG/SPINK1 immunohistochemistry.Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc · 2016
    Article
  14. Article
  15. Review
  16. Review
  17. Prostate cancer: a review of active surveillance.Research and reports in urology · 2014
    Review
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Eric A SingerUrologic Oncology Branch, Center for Cancer Research, Division of Cancer Prevention, National Cancer Institute, Bethesda, Maryland, United States.
Aradhana Kaushal
Baris Turkbey
Anna Couvillon
Peter A Pinto
Howard L Parnes

Funding

Clinical Nursing and Data Management CoreZIDBC011089 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI LINEHAN, WILLIAM MARSTON · 2009 to 2025
$17.4M
Prostate SectionZIABC011081 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI PINTO, PETER · 2009 to 2025
$15.2M
Clinical Fellowship Training ProgramZIEBC011023 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI PINTO, PETER · 2009 to 2025
$10.3M
Prostate SectionZ01BC011081 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI PINTO, PETER · 2008 to 2008
$99k
Intramural NIH HHS Z01 BC011081Intramural NIH HHS ZIA BC011081Intramural NIH HHS ZID BC011089Intramural NIH HHS ZIE BC011023
6 · The paper itself

Abstract

purpose of reviewThis article reviews recent developments in the use of active surveillance for localized prostate cancer. RECENT

findingsThe treatment of localized prostate cancer continues to be a major challenge for urologic oncologists. Screening with prostate-specific antigen has resulted in increased numbers of low-risk prostate cancers being detected. Aggressive whole-gland therapy with surgery, or radiation therapy is associated with potentially life-altering treatment-related side effects such as urinary incontinence, bowel toxicity and erectile dysfunction. The goal of active surveillance is to avoid or delay the adverse events associated with prostate cancer therapy while still allowing for curative intervention in the future, if needed. SUMMARY: Active surveillance is a reasonable treatment option for many men with low-risk, and some men with intermediate-risk, prostate cancer. Additional research is needed to determine the optimal active surveillance inclusion criteria, monitoring schedule, and treatment triggers. It is hoped that advances in prostate imaging, biomarkers, and focal therapy will foster greater use of active surveillance in appropriately selected men to optimize quality-of-life without compromising cancer outcomes.

Indexed as

Population SurveillanceQuality of LifeWatchful WaitingBiomarkers, TumorEarly DiagnosisErectile DysfunctionHumansMalePatient SelectionProstatectomyProstate-Specific AntigenProstatic NeoplasmsBiomarkers, TumorProstate-Specific Antigen

Identifiers

PMID22450149
PMCPMC7473449

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.