Joy returns last: anhedonia and treatment resistance in depressed adolescents.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

11 citing papers in PubMed.

1. The prefrontal-striatal signatures of reduced model-based learning in depressed patients.Annals of general psychiatry · 2026
   Article
2. Synaptotagmin-4 induces anhedonic responses to chronic stress via BDNF signaling in the medial prefrontal cortex.Experimental & molecular medicine · 2024
   Article
3. Active versus sham DLPFC-NAc rTMS for depressed adolescents with anhedonia using resting-state functional magnetic resonance imaging (fMRI): a study protocol for a randomized placebo-controlled trial.Trials · 2024
   Article
4. Chronic unpredictable stress induces depression-related behaviors by suppressing AgRP neuron activity.Molecular psychiatry · 2021
   Article
5. Does Desire to Pursue Pleasurable Activities Matter? The Impact of Pretransplantation Anhedonia on Quality of Life and Fatigue in Hematopoietic Stem Cell Transplantation.Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation · 2020
   Article
6. Anhedonia and Increased Evoked Immune Response.Brain, behavior, & immunity - health · 2020
   Article
7. The Measurement of Positive Valence Forms of Empathy and Their Relation to Anhedonia and Other Depressive Symptomatology.Frontiers in psychology · 2019
   Article
8. Targeting opioid receptor signaling in depression: do we need selective κ opioid receptor antagonists?Neuronal signaling · 2018
   Review
9. Neurobiology of hedonic tone: the relationship between treatment-resistant depression, attention-deficit hyperactivity disorder, and substance abuse.Neuropsychiatric disease and treatment · 2016
   Review
10. Opioid hedonic hotspot in nucleus accumbens shell: mu, delta, and kappa maps for enhancement of sweetness "liking" and "wanting".The Journal of neuroscience : the official journal of the Society for Neuroscience · 2014
    Article
11. Anhedonia: a concept analysis.Archives of psychiatric nursing · 2013
    Review

Corrections and comments

• Comment on
  Anhedonia predicts poorer recovery among youth with selective serotonin reuptake inhibitor treatment-resistant depression.2012

Authors and funding

1 author.

Funding

No grant is acknowledged in the PubMed record.

Abstract

PubMed holds no abstract for this paper.

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