Evidence map›Paper›PMID 22449625›Full record

ReviewSeminars in hematology2012

Evaluation and differential diagnosis of marked, persistent eosinophilia.

Rojelio Mejia, Thomas B Nutman

Abstract readReview
In one paragraph

Review in Seminars in hematology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
4.4field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 97 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
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  11. Article
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  15. Article
  16. An Integrated Study ofTropical medicine and infectious disease · 2020
    Article
  17. Article
  18. Ascites in a 21-year-old man.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2019
    Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Rojelio MejiaLaboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892-0425, USA.
Thomas B Nutman
National Institute of Allergy and Infectious Diseases · USNational Institutes of Health · US

Funding

Clinical And Therapeutic Studies Of Human Filariasis and Related DiseasesZIAAI000439 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI NUTMAN, THOMAS · 2009 to 2025
$14.8M
Th2-associated responses and their control in parasitic helminth infections and related disordersZIAAI000805 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI NUTMAN, THOMAS · 2009 to 2024
$4.4M
Immediate Hypersensitivity Responses-Infections ControlZ01AI000805 · NIAID · NIAID EXTRAMURAL ACTIVITIES · PI NUTMAN, THOMAS B · 1997 to 2008
$1.1M
Intramural NIH HHS Z01 AI000805
6 · The paper itself

Abstract

High-grade eosinophilia can be a diagnostic dilemma, as the etiologies are extensive and varied. Hypereosinophilic syndromes (HES) are a group of heterogeneous disorders, many of which remain poorly defined. By definition, HES must be distinguished from other disorders with persistently elevated eosinophilia with a defined cause. Although marked eosinophilia worldwide is most commonly caused by helminth (worm) infections, non-infectious causes must be considered, and include drug reactions, malignancies, and immunologic, inflammatory and allergic diseases.

Indexed as

AnimalsDiagnosis, DifferentialHumansHypereosinophilic SyndromeHypersensitivityInflammation

Identifiers

PMID22449625
PMCPMC3314223
OpenAlexW2041597386

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.