Evidence map›Paper›PMID 22449190›Full record

ReviewEpigenomics2012

Epigenomics of idiopathic pulmonary fibrosis.

Ivana V Yang

Open access · greenAbstract readReview
In one paragraph

Review in Epigenomics, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
5.4field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it, 50 citations in OpenAlex.

  1. Fibrotic interstitial lung diseases and air pollution: a systematic literature review.European respiratory review : an official journal of the European Respiratory Society · 2020
    Pooled it
  2. Review
  3. Review
  4. Review
  5. Article
  6. Article
  7. Review
  8. Review
  9. Review
  10. Article
  11. Smoking and interstitial lung diseases.European respiratory review : an official journal of the European Respiratory Society · 2015
    Review
  12. Review
  13. Idiopathic pulmonary fibrosis and sleep disorders: no longer strangers in the night.European respiratory review : an official journal of the European Respiratory Society · 2015
    Review
  14. Article
  15. Genetic susceptibility and pulmonary fibrosis.Current opinion in pulmonary medicine · 2014
    Review
  16. Review
  17. Integrating omics technologies to study pulmonary physiology and pathology at the systems level.Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology · 2014
    Review
  18. Review
  19. Idiopathic pulmonary fibrosis: the need for early diagnosis.Multidisciplinary respiratory medicine · 2013
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Ivana V YangCenter for Genes, Environment & Health & the Department of Medicine, National Jewish Health, Denver, CO, USA. ivana.yang@ucdenver.edu
National Jewish Health · US

Funding

Lung Genomics Research ConsortiumRC2HL101715 · NHLBI · UNIVERSITY OF COLORADO DENVER · PI GERACI, MARK W, KAMINSKI, NAFTALI · 2009 to 2010
$11.4M
NHLBI NIH HHS RC2 HL101715
6 · The paper itself

Abstract

Idiopathic pulmonary fibrosis (IPF) is a complex lung disease of unknown etiology. Development of IPF is influenced by both genetic and environmental factors. Gene-expression profiling studies have taught us quite a bit about the biology of this fatal disease, but epigenetic marks may be the missing link that connects the environmental exposure in genetically predisposed individuals to transcriptome changes associated with the development of IPF. This review will begin with an introduction to the disease, followed by brief summaries of studies of gene expression in IPF and epigenetic marks associated with exposures relevant to IPF. The majority of the discussion will focus on epigenetic studies conducted so far in IPF, the limitations, challenges nd future directions in this field.

Indexed as

EpigenomicsDNA MethylationGene Expression ProfilingHistonesHumansIdiopathic Pulmonary FibrosisMicroRNAsSmokingHistonesMicroRNAs

Identifiers

PMID22449190
PMCPMC3412586
OpenAlexW2119627031

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.