ArticleMalaria journal2012
Exploiting the behaviour of wild malaria vectors to achieve high infection with fungal biocontrol agents.
Article in Malaria journal, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.
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Who cites it
40 citing papers in PubMed.
- Development of Mycoinsecticides: Advances in Formulation, Regulatory Challenges and Market Trends for Entomopathogenic Fungi.Journal of fungi (Basel, Switzerland) · 2025Review
- Malaria-Transmitting Vectors Microbiota: Overview and Interactions WithFrontiers in microbiology · 2022Review
- The interplay between dose and immune system activation determines fungal infection outcome in the African malaria mosquito, Anopheles gambiae.Developmental and comparative immunology · 2018Article
- Impact of partially and fully closed eaves on house entry rates by mosquitoes.Parasites & vectors · 2018Article
- Improving the delivery and efficiency of fungus-impregnated cloths for control of adult Aedes aegypti using a synthetic attractive lure.Parasites & vectors · 2018Article
- Wash-resistance of pirimiphos-methyl insecticide treatments of window screens and eave baffles for killing indoor-feeding malaria vector mosquitoes: an experimental hut trial, South East of Zambia.Malaria journal · 2018Article
- Keeping track of mosquitoes: a review of tools to track, record and analyse mosquito flight.Parasites & vectors · 2018Review
- Biological control of human disease vectors: a perspective on challenges and opportunities.BioControl (Dordrecht, Netherlands) · 2018Review
- Experimental evolution to increase the efficacy of the entomopathogenic fungusEvolutionary applications · 2017Article
- The paradigm of eave tubes: scaling up house improvement and optimizing insecticide delivery against disease-transmitting mosquitoes.Malaria journal · 2017Article
- Control of Malaria Vector Mosquitoes by Insecticide-Treated Combinations of Window Screens and Eave Baffles.Emerging infectious diseases · 2017Article
- Measuring, manipulating and exploiting behaviours of adult mosquitoes to optimise malaria vector control impact.BMJ global health · 2017Article
- Developing an expanded vector control toolbox for malaria elimination.BMJ global health · 2017Article
- Comparative genomics of Beauveria bassiana: uncovering signatures of virulence against mosquitoes.BMC genomics · 2016Article
- Visualization of house-entry behaviour of malaria mosquitoes.Malaria journal · 2016Article
- Most outdoor malaria transmission by behaviourally-resistant Anopheles arabiensis is mediated by mosquitoes that have previously been inside houses.Malaria journal · 2016Article
- Development and evaluation of mosquito-electrocuting traps as alternatives to the human landing catch technique for sampling host-seeking malaria vectors.Malaria journal · 2015Article
- Effects of a new outdoor mosquito control device, the mosquito landing box, on densities and survival of the malaria vector, Anopheles arabiensis, inside controlled semi-field settings.Malaria journal · 2015Article
- The potential for fungal biopesticides to reduce malaria transmission under diverse environmental conditions.The Journal of applied ecology · 2015Article
- Crepuscular Behavioral Variation and Profiling of Opsin Genes in Anopheles gambiae and Anopheles stephensi (Diptera: Culicidae).Journal of medical entomology · 2015Article
Corrections and comments
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundControl of mosquitoes that transmit malaria has been the mainstay in the fight against the disease, but alternative methods are required in view of emerging insecticide resistance. Entomopathogenic fungi are candidate alternatives, but to date, few trials have translated the use of these agents to field-based evaluations of their actual impact on mosquito survival and malaria risk. Mineral oil-formulations of the entomopathogenic fungi Metarhizium anisopliae and Beauveria bassiana were applied using five different techniques that each exploited the behaviour of malaria mosquitoes when entering, host-seeking or resting in experimental huts in a malaria endemic area of rural Tanzania.
resultsSurvival of mosquitoes was reduced by 39-57% relative to controls after forcing upward house-entry of mosquitoes through fungus treated baffles attached to the eaves or after application of fungus-treated surfaces around an occupied bed net (bed net strip design). Moreover, 68 to 76% of the treatment mosquitoes showed fungal growth and thus had sufficient contact with fungus treated surfaces. A population dynamic model of malaria-mosquito interactions shows that these infection rates reduce malaria transmission by 75-80% due to the effect of fungal infection on adult mortality alone. The model also demonstrated that even if a high proportion of the mosquitoes exhibits outdoor biting behaviour, malaria transmission was still significantly reduced.
conclusionsEntomopathogenic fungi strongly affect mosquito survival and have a high predicted impact on malaria transmission. These entomopathogens represent a viable alternative for malaria control, especially if they are used as part of an integrated vector management strategy.
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