ArticleTheScientificWorldJournal2012
Thyroid function after subtotal thyroidectomy in patients with Graves' hyperthyroidism.
Article in TheScientificWorldJournal, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed, 21 citations in OpenAlex.
- Mechanisms and Treatment Options for Hyperthyroid-Induced Osteoporosis: A Narrative Review.Cureus · 2023Review
- A Case of Recurrent Thyrotoxicosis in a Thyroglossal Duct Cyst 18 Years Following Thyroid Surgery.Cureus · 2023Article
- Carbimazole-Induced Agranulocytosis in a Previously Stable Patient: A Case Report and Literature Review.Cureus · 2022Article
- Short-Term Outcomes of Surgery for Graves' Disease in Germany.Journal of clinical medicine · 2020Article
- Microencapsulation of porcine thyroid cell organoids within a polymer microcapsule construct.Experimental biology and medicine (Maywood, N.J.) · 2017Article
- Hypothyroidism after a cancer diagnosis: etiology, diagnosis, complications, and management.The oncologist · 2014Review
- Retrospective Study of Tc-99m Thyroid Scan in Patients with Graves' Disease: Is There Significant Difference in Lobar Activity?Indian journal of nuclear medicine : IJNM : the official journal of the Society of Nuclear Medicine, IndiaArticle
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSubtotal thyroidectomy is a surgical procedure, in which the surgeon leaves a small thyroid remnant in situ to preserve thyroid function, thereby preventing lifelong thyroid hormone supplementation therapy.
aimTo evaluate thyroid function after subtotal thyroidectomy for Graves' hyperthyroidism. SUBJECTS AND
methodsWe retrospectively reviewed the medical records of all patients (n = 62) who underwent subtotal thyroidectomy for recurrent Graves' hyperthyroidism between 1992 and 2008 in our hospital. Thyroid function was defined according to plasma TSH and free T4 values.
resultsMedian followup after operation was 54.6 months (range 2.1-204.2 months). Only 6% of patients were euthyroid after surgery. The majority of patients (84%) became hypothyroid, whereas 10% of patients had persistent or recurrent hyperthyroidism. Permanent recurrent laryngeal nerve palsy and permanent hypocalcaemia were noted in 1.6% and 3.2% of patients, respectively.
conclusionIn our series, subtotal thyroidectomy for Graves' hyperthyroidism was associated with a high risk of postoperative hypothyroidism and a smaller, but significant, risk of persistent hyperthyroidism. Our data suggest that subtotal thyroidectomy seems to provide very little advantage over total thyroidectomy in terms of postoperative thyroid function.
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