Evidence map›Paper›PMID 22447230›Full record

ReviewJournal of cardiovascular translational research2012

Haptoglobin genotype and its role in diabetic cardiovascular disease.

Tina Costacou, Andrew P Levy

Abstract readReview
In one paragraph

Review in Journal of cardiovascular translational research, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
2.0field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 55 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 2 countries.

Tina CostacouDepartment of Epidemiology, University of Pittsburgh, Pittsburgh, PA 15213, USA. costacout@edc.pitt.edu
Andrew P Levy
Technion – Israel Institute of Technology · ILUniversity of Pittsburgh · US

Funding

The Oxidation Hypothesis Revisited:Haptoglobin Genotype and Diabetic AtheroscleroR01DK085226 · NIDDK · TECHNION-ISRAEL INSTITUTE OF TECHNOLOGY · PI LEVY, ANDREW PETER · 2009 to 2013
$664k
Oxidative insults, antioxidative responses and type 1 diabetes complicationsR21DK082900 · NIDDK · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI COSTACOU, TINA · 2009 to 2010
$409k
NIDDK NIH HHS DK082900NIDDK NIH HHS R01 DK085226NIDDK NIH HHS R01DK085226NIDDK NIH HHS R21 DK082900
6 · The paper itself

Abstract

Over the past decade, several longitudinal epidemiological studies have brought attention to the haptoglobin genotype and its importance in determining diabetic vascular disease risk. This manuscript presents an overview of the biology of the haptoglobin genotype and reviews the literature concerning its role in the development of cardiovascular disease among individuals with diabetes mellitus.

Indexed as

Polymorphism, GeneticAnimalsCardiovascular DiseasesDiabetes ComplicationsDiabetes MellitusDiabetic AngiopathiesGenetic Predisposition to DiseaseHaptoglobinsHumansIncidencePhenotypePrognosisProtein ConformationRisk AssessmentRisk FactorsStructure-Activity RelationshipHaptoglobinsHP protein, human

Identifiers

PMID22447230
PMCPMC3595557
OpenAlexW2098267944

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.