Evidence map›Paper›PMID 22447132›Full record

ReviewCurrent pain and headache reports2012

The bowel and migraine: update on celiac disease and irritable bowel syndrome.

Roger K Cady, Kathleen Farmer, J Kent Dexter, Jessica Hall

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current pain and headache reports, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Review
  8. Review
  9. Review
  10. Article
  11. Review
  12. A Clinical Approach to Addressing Diet with Migraine Patients.Current neurology and neuroscience reports · 2017
    Review
  13. Article
  14. Gastrointestinal Headache; a Narrative Review.Emergency (Tehran, Iran) · 2016
    Review
  15. Review
  16. What the Gut Can Teach Us About Migraine.Current pain and headache reports · 2015
    Review
  17. Review
  18. Review
  19. Clinical features and symptom recovery on a gluten-free diet in Canadian adults with celiac disease.Canadian journal of gastroenterology = Journal canadien de gastroenterologie · 2013
    Article
  20. Irritable bowel syndrome and migraine: bystanders or partners?Journal of neurogastroenterology and motility · 2013
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Roger K CadyHeadache Care Center, 3805 South Kansas Expressway, Springfield, MO 65807, USA. rcady@banyangroupinc.com
Kathleen Farmer
J Kent Dexter
Jessica Hall

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This article explores possible relationships between migraine, irritable bowel syndrome (IBS), celiac disease (CD), and gluten sensitivity. These seemingly distinct medical entities curiously share many common epidemiological, psychosocial, and pathophysiological similarities. Considerable evidence is emerging to support a concept that experiencing significant threatening adverse events creates a state of hypervigilance in the nervous system, which associates with exaggerated response to future threats and episodic attacks of migraine and IBS. While this sensitizing response is generally considered to reside in the central nervous system, it may be possible that the initiation resides in the enteric nervous system as well. What appears to link migraine, IBS, and CD is a disease model of a genetically sensitive nervous system transformed into one that is hypervigilant, and that over time can often develop disabling and pervasive disease.

Indexed as

Celiac DiseaseComorbidityDiet, Gluten-FreeEnteric Nervous SystemFemaleHumansIrritable Bowel SyndromeMaleMigraine DisordersReceptors, SerotoninReceptors, Serotonin

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.