ArticleCommunicative & integrative biology2011
Evolution of sodium channels and the new view of early nervous system evolution.
Article in Communicative & integrative biology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
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Who cites it
8 citing papers in PubMed, 12 citations in OpenAlex.
- Growth produces coordination trade-offs inProceedings of the National Academy of Sciences of the United States of America · 2023Article
- Reconstruction of protein domain evolution using single-cell amplified genomes of uncultured choanoflagellates sheds light on the origin of animals.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2019Article
- Co-expression of synaptic genes in the sponge Amphimedon queenslandica uncovers ancient neural submodules.Scientific reports · 2019Article
- Small molecule modulation of voltage gated sodium channels.Current opinion in structural biology · 2017Review
- Complex Homology and the Evolution of Nervous Systems.Trends in ecology & evolution · 2016Review
- A customized Web portal for the genome of the ctenophore Mnemiopsis leidyi.BMC genomics · 2014Article
- Phylogeny unites animal sodium leak channels with fungal calcium channels in an ancient, voltage-insensitive clade.Molecular biology and evolution · 2012Article
- Adaptive evolution of voltage-gated sodium channels: the first 800 million years.Proceedings of the National Academy of Sciences of the United States of America · 2012Review
Corrections and comments
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Authors and funding
1 author at 1 institution in 1 country.
Funding
Abstract
Advances in genomics have revealed that many genes implicated in the nervous systems of bilaterians were already present in the last common ancestor (LCA) of animals, and some even before that.(1) (-) (5) This new information coincides with a growing reinterpretation of cnidarian nervous systems which holds that they are 'fundamentally conventional' with regards to bilaterian nervous systems,(6) and do not represent ancient forms. Since in general adult forms are expected to be the most derived features of organisms, the study of non-bilaterian larval forms may be a better way to investigate potential plesiomorphies. We recently showed that voltage-gated sodium channel (Na(v)) genes, which make action potentials in nerves and muscles, were present in the LCA of animals and choanoflagellates, the closest unicellular relatives to animals.(2) This addendum will attempt to put this finding within the context of the new views of nervous system evolution.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.